Pharmacological comparison of human homomeric 5-HT_3A receptors versus heteromeric 5-HT_3A/3B receptors
Research output: Contribution to journal › Article
The present study determined the detailed pharmacological profile of heterologously expressed human (h) homomeric 5-HT3A receptors in direct comparison to heteromeric h5-HT3A/3B receptors. The very minor differences in their respective pharmacological profiles indicates that the 5-HT3B receptor subunit alters, predominantly, the biophysical rather than the pharmacological properties of the 5-HT3 receptor. (C) 2001 Elsevier Science Ltd. All rights reserved.
|Number of pages||3|
|Publication status||Published - 1 Aug 2001|
- 5-HT3 receptor, 5-HT3B subunit, ligand-gated ion channel, 5-HT3A subunit