Pharmacological comparison of human homomeric 5-HT_3A receptors versus heteromeric 5-HT_3A/3B receptors

Research output: Contribution to journalArticle


The present study determined the detailed pharmacological profile of heterologously expressed human (h) homomeric 5-HT3A receptors in direct comparison to heteromeric h5-HT3A/3B receptors. The very minor differences in their respective pharmacological profiles indicates that the 5-HT3B receptor subunit alters, predominantly, the biophysical rather than the pharmacological properties of the 5-HT3 receptor. (C) 2001 Elsevier Science Ltd. All rights reserved.


Original languageEnglish
Pages (from-to)282-284
Number of pages3
Issue number2
Publication statusPublished - 1 Aug 2001


  • 5-HT3 receptor, 5-HT3B subunit, ligand-gated ion channel, 5-HT3A subunit