Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography

Research output: Contribution to journalArticlepeer-review

Standard

Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography. / Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants ; Belli, Tony.

In: Journal of neurosurgery. Pediatrics, Vol. 27, No. 5, 05.2021, p. 538–547.

Research output: Contribution to journalArticlepeer-review

Harvard

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants & Belli, T 2021, 'Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography', Journal of neurosurgery. Pediatrics, vol. 27, no. 5, pp. 538–547. https://doi.org/10.3171/2020.9.PEDS20421

APA

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants, & Belli, T. (2021). Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography. Journal of neurosurgery. Pediatrics, 27(5), 538–547. https://doi.org/10.3171/2020.9.PEDS20421

Vancouver

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants, Belli T. Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography. Journal of neurosurgery. Pediatrics. 2021 May;27(5):538–547. https://doi.org/10.3171/2020.9.PEDS20421

Author

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants ; Belli, Tony. / Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography. In: Journal of neurosurgery. Pediatrics. 2021 ; Vol. 27, No. 5. pp. 538–547.

Bibtex

@article{b4fbcb1b207e4ea68e2ae763f1fc959e,
title = "Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography",
abstract = "OBJECTIVE: The aim of this paper was to evaluate the prevalence of postconcussive symptoms and their relation to health-related quality of life (HRQOL) in pediatric and adolescent patients with mild traumatic brain injury (mTBI) who received head CT imaging during initial assessment.METHODS: Patients aged between 5 and 21 years with mTBI (Glasgow Coma Scale scores 13-15) and available Rivermead Post Concussion Questionnaire (RPQ) at 6 months of follow-up in the multicenter, prospectively collected CENTER-TBI (Collaborative European NeuroTrauma Effectiveness Research in TBI) study were included. The prevalence of postconcussive symptoms was assessed, and the occurrence of postconcussive syndrome (PSC) based on the ICD-10 criteria, was analyzed. HRQOL was compared in patients with and without PCS using the Quality of Life after Brain Injury (QOLIBRI) questionnaire.RESULTS: A total of 196 adolescent or pediatric mTBI patients requiring head CT imaging were included. High-energy trauma was prevalent in more than half of cases (54%), abnormalities on head CT scans were detected in 41%, and admission to the regular ward or intensive care unit was necessary in 78%. Six months postinjury, 36% of included patients had experienced at least one moderate or severe symptom on the RPQ. PCS was present in 13% of adolescents and children when considering symptoms of at least moderate severity, and those patients had significantly lower QOLIBRI total scores, indicating lower HRQOL, compared with young patients without PCS (57 vs 83 points, p < 0.001).CONCLUSIONS: Adolescent and pediatric mTBI patients requiring head CT imaging show signs of increased trauma severity. Postconcussive symptoms are present in up to one-third of those patients, and PCS can be diagnosed in 13% 6 months after injury. Moreover, PCS is significantly associated with decreased HRQOL.",
keywords = "CT imaging, HRQOL, Health-related quality of life, Mild traumatic brain injury, Pediatric, Postconcussive symptoms, RPQ, Rivermead Post Concussion Symptoms Questionnaire, Trauma",
author = "{Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants} and Lennart Riemann and Voormolen, {Daphne C} and Katrin Rauen and Klaus Zweckberger and Andreas Unterberg and Alexander Younsi and Tony Belli",
year = "2021",
month = may,
doi = "10.3171/2020.9.PEDS20421",
language = "English",
volume = "27",
pages = "538–547",
journal = "Journal of neurosurgery. Pediatrics",
issn = "1933-0707",
publisher = "American Association of Neurological Surgeons",
number = "5",

}

RIS

TY - JOUR

T1 - Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography

AU - Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants

AU - Riemann, Lennart

AU - Voormolen, Daphne C

AU - Rauen, Katrin

AU - Zweckberger, Klaus

AU - Unterberg, Andreas

AU - Younsi, Alexander

AU - Belli, Tony

PY - 2021/5

Y1 - 2021/5

N2 - OBJECTIVE: The aim of this paper was to evaluate the prevalence of postconcussive symptoms and their relation to health-related quality of life (HRQOL) in pediatric and adolescent patients with mild traumatic brain injury (mTBI) who received head CT imaging during initial assessment.METHODS: Patients aged between 5 and 21 years with mTBI (Glasgow Coma Scale scores 13-15) and available Rivermead Post Concussion Questionnaire (RPQ) at 6 months of follow-up in the multicenter, prospectively collected CENTER-TBI (Collaborative European NeuroTrauma Effectiveness Research in TBI) study were included. The prevalence of postconcussive symptoms was assessed, and the occurrence of postconcussive syndrome (PSC) based on the ICD-10 criteria, was analyzed. HRQOL was compared in patients with and without PCS using the Quality of Life after Brain Injury (QOLIBRI) questionnaire.RESULTS: A total of 196 adolescent or pediatric mTBI patients requiring head CT imaging were included. High-energy trauma was prevalent in more than half of cases (54%), abnormalities on head CT scans were detected in 41%, and admission to the regular ward or intensive care unit was necessary in 78%. Six months postinjury, 36% of included patients had experienced at least one moderate or severe symptom on the RPQ. PCS was present in 13% of adolescents and children when considering symptoms of at least moderate severity, and those patients had significantly lower QOLIBRI total scores, indicating lower HRQOL, compared with young patients without PCS (57 vs 83 points, p < 0.001).CONCLUSIONS: Adolescent and pediatric mTBI patients requiring head CT imaging show signs of increased trauma severity. Postconcussive symptoms are present in up to one-third of those patients, and PCS can be diagnosed in 13% 6 months after injury. Moreover, PCS is significantly associated with decreased HRQOL.

AB - OBJECTIVE: The aim of this paper was to evaluate the prevalence of postconcussive symptoms and their relation to health-related quality of life (HRQOL) in pediatric and adolescent patients with mild traumatic brain injury (mTBI) who received head CT imaging during initial assessment.METHODS: Patients aged between 5 and 21 years with mTBI (Glasgow Coma Scale scores 13-15) and available Rivermead Post Concussion Questionnaire (RPQ) at 6 months of follow-up in the multicenter, prospectively collected CENTER-TBI (Collaborative European NeuroTrauma Effectiveness Research in TBI) study were included. The prevalence of postconcussive symptoms was assessed, and the occurrence of postconcussive syndrome (PSC) based on the ICD-10 criteria, was analyzed. HRQOL was compared in patients with and without PCS using the Quality of Life after Brain Injury (QOLIBRI) questionnaire.RESULTS: A total of 196 adolescent or pediatric mTBI patients requiring head CT imaging were included. High-energy trauma was prevalent in more than half of cases (54%), abnormalities on head CT scans were detected in 41%, and admission to the regular ward or intensive care unit was necessary in 78%. Six months postinjury, 36% of included patients had experienced at least one moderate or severe symptom on the RPQ. PCS was present in 13% of adolescents and children when considering symptoms of at least moderate severity, and those patients had significantly lower QOLIBRI total scores, indicating lower HRQOL, compared with young patients without PCS (57 vs 83 points, p < 0.001).CONCLUSIONS: Adolescent and pediatric mTBI patients requiring head CT imaging show signs of increased trauma severity. Postconcussive symptoms are present in up to one-third of those patients, and PCS can be diagnosed in 13% 6 months after injury. Moreover, PCS is significantly associated with decreased HRQOL.

KW - CT imaging

KW - HRQOL

KW - Health-related quality of life

KW - Mild traumatic brain injury

KW - Pediatric

KW - Postconcussive symptoms

KW - RPQ

KW - Rivermead Post Concussion Symptoms Questionnaire

KW - Trauma

U2 - 10.3171/2020.9.PEDS20421

DO - 10.3171/2020.9.PEDS20421

M3 - Article

C2 - 33636701

VL - 27

SP - 538

EP - 547

JO - Journal of neurosurgery. Pediatrics

JF - Journal of neurosurgery. Pediatrics

SN - 1933-0707

IS - 5

ER -