Persistence of fetal cells in the mother: friend or foe?

Research output: Contribution to journalArticle

Abstract

There is increasing evidence that both circulating cells and free fetal DNA persist in the maternal circulation after delivery of the fetus. In some cases, this has been described many years after the end of the pregnancy. This article reviews the evidence for these cells being present, the potential methodologies used to identify such cells and the potential effects on maternal immunomodulation. Data relating to the potential beneficial and potentially harmful effects are discussed.

Details

Original languageEnglish
Pages (from-to)1321-5
Number of pages5
JournalBJOG
Volume114
Issue number11
Publication statusPublished - 1 Nov 2007

Keywords

  • fetus, immunology, cell