Patient with liver dysfunction while maintained on veno-venous extracorporeal membrane oxygenation should not be overlooked as a potential donor

Moustafa M Mourad, Michael Reay, Paolo Muiesan, Darius F Mirza, M Thamara P R Perera

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

This report describes transplantation of liver allograft from a circulatory death donor who was supported by veno-venous extracorporeal membrane oxygenation (ECMO) for 14 days and presented with severely altered liver functions. Successful liver transplant was done in a patient with hepatocellular carcinoma (HCC) in the background of primary sclerosing cholangitis. There was immediate graft function and uneventful recovery with stable graft function at 1-year follow-up. This case illustrates the ability of veno-venous ECMO to resuscitate organs in the presence of severe dysfunction, and perhaps, lessons from this case may be incorporated to optimize the condition of organs rescued from these marginal donors and exemplify the use of ECMO in normothermic regional perfusion in donors after circulatory death.

Original languageEnglish
Pages (from-to)e50-e53
Number of pages4
JournalTransplant international
Volume27
Issue number6
Early online date21 Feb 2014
DOIs
Publication statusPublished - 1 Jun 2014

Keywords

  • Adult
  • Disease Progression
  • Extracorporeal Membrane Oxygenation
  • Follow-Up Studies
  • Graft Survival
  • Heart Arrest
  • Humans
  • Liver Diseases
  • Liver Transplantation
  • Living Donors
  • Middle Aged
  • Pulmonary Fibrosis
  • Respiratory Insufficiency
  • Risk Assessment
  • Tissue and Organ Procurement
  • Transplant Recipients
  • Treatment Outcome
  • donor after circulatory death
  • graft dysfunction
  • marginal donor

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