Panniculitis secondary to extravasation of clarithromycin in a patient with alpha-1-antitrypsin deficiency (phenotype PiZ)
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Colleges, School and Institutes
alpha 1-Antitrypsin deficiency (AATD) is known to be associated with panniculitis. Although reports of this association are rare, the true incidence may be unappreciated because of underdiagnosis of AATD. We report a case of panniculitis occurring in a 34-year-old woman with severe AATD following the extravasation of clarithromycin infused intravenously for treatment of community-acquired pneumonia. Resolution occurred with conservative management. The histopathology and management of this unusual condition are discussed, with a review of the literature.
|Number of pages||4|
|Journal||British Journal of Dermatology|
|Publication status||Published - 1 Aug 2003|