Abstract
Introduction
Idiopathic Intracranial Hypertension is condition characterised by raised intracranial pressure, papilledema, and normal neuroimaging (aside from radiological signs of raised intracranial pressure). Symptoms of idiopathic intracranial hypertension include chronic headaches and for some, visual loss. New treatments are an unmet clinical need.
Areas covered
The aim of this review is to present the evidence base and considered opinion on outcome measures to determine successful management of idiopathic intracranial hypertension.
Expert opinion
Less invasive measures of disease activity such as optical coherence tomography will continue to grow in this field, both as a measure of papilledema, and potentially as a surrogate for intracranial pressure and visual function. As a highly disabling aspect of the disease is headache, treatment outcomes for headache morbidity need to be appropriately chosen and standardized to allow comparison between trials.
Idiopathic Intracranial Hypertension is condition characterised by raised intracranial pressure, papilledema, and normal neuroimaging (aside from radiological signs of raised intracranial pressure). Symptoms of idiopathic intracranial hypertension include chronic headaches and for some, visual loss. New treatments are an unmet clinical need.
Areas covered
The aim of this review is to present the evidence base and considered opinion on outcome measures to determine successful management of idiopathic intracranial hypertension.
Expert opinion
Less invasive measures of disease activity such as optical coherence tomography will continue to grow in this field, both as a measure of papilledema, and potentially as a surrogate for intracranial pressure and visual function. As a highly disabling aspect of the disease is headache, treatment outcomes for headache morbidity need to be appropriately chosen and standardized to allow comparison between trials.
| Original language | English |
|---|---|
| Pages (from-to) | 687-700 |
| Journal | Expert Review of Neurotherapeutics |
| Volume | 21 |
| Issue number | 6 |
| Early online date | 28 May 2021 |
| DOIs | |
| Publication status | E-pub ahead of print - 28 May 2021 |
Keywords
- Idiopathic intracranial hypertension
- headache
- intracranial pressure
- obesity
- optical coherence tomography
- papilledema
- pseudotumour cerebri
- randomized control trial
- vision and weight loss
ASJC Scopus subject areas
- General Neuroscience
- Clinical Neurology
- Pharmacology (medical)