Optically pure bulky (hetero)arylalkyl carbinols via kinetic resolution

Research output: Contribution to journalArticle

Authors

  • Bin Hu
  • Meng Meng
  • Weimin Mo
  • Xinquan Hu
  • Wei-Ping Deng

Colleges, School and Institutes

Abstract

Planar chiral nucleophilic catalyst Fc-PIP was employed in the kinetic resolution of bulky (hetero)arylalkyl carbinols delivering unreacted alcohols with extremely high enantiomeric excess (>99.0% ees) in ideal conversions ranging from 50.4-56.7%.

Details

Original languageEnglish
Pages (from-to)10632-4
Number of pages3
JournalChemical Communications
Volume47
Issue number38
Publication statusPublished - 2011