Optical coherence tomography confirms shunt malfunction and recurrence of raised intracranial pressure in optic atrophy

Research output: Contribution to journalArticlepeer-review

Authors

  • Ahoane Qureshi
  • Jasvir Virdee
  • Georgios Tsermoulas
  • Alex Sinclair
  • Susan Mollan

Colleges, School and Institutes

Abstract

Background: Investigating potential cerebrospinal fluid (CSF) shunt malfunction can be a challenge. Optical coherence tomography (OCT), a non-invasive imaging technique, is used to monitor changes at the optic nerve head in papilloedema. Conventional teaching suggests that in the presence of optic atrophy the optic nerve head may not re-swell in response to a relapse in raised intracranial pressure (ICP). 

Methods: A retrospective case series of three patients who had prior CSF diversion surgery for idiopathic intracranial cranial hypertension (IIH) is presented demonstrating the benefit of non-invasive OCT imaging confirming raised ICP. 

Results: Recurrence of raised ICP, due to malfunctioning CSF shunt, was diagnosed in three patients requiring further surgical intervention. All re-presented acutely with headache and visual disturbances. All had a prior diagnosis of optic atrophy. In all patients, OCT peripapillary retinal nerve fibre layer qualitative image analysis and quantified progression analysis permitted easy detection of the recurrence of papilloedema. 

Conclusion: OCT imaging supports clinical decision making in shunt malfunction, even in the presence of established optic atrophy secondary to IIH.

Details

Original languageEnglish
JournalBritish Journal of Neurosurgery
Early online date6 Nov 2020
Publication statusE-pub ahead of print - 6 Nov 2020

Keywords

  • Cerebrospinal fluid diversion, idiopathic intracranial hypertension, optic atrophy, optical coherence tomography, papilloedema, pseudotumour cerebri, shunts

ASJC Scopus subject areas