"Omics" approaches in the context of environmental toxicology

Research output: Chapter in Book/Report/Conference proceedingChapter


  • Jon C. Cook
  • Nancy D. Denslow
  • Taisen Iguchi
  • Elwood A. Linney
  • Ann Miracle
  • Timothy R. Zacharewski

Colleges, School and Institutes

External organisations

  • Pfizer Inc.
  • University of Florida
  • Okazaki National Research Institutes
  • Duke University
  • U.S. Environmental Protection Agency
  • Dartmouth College
  • Michigan State University


The goals of this chapter are to 1) introduce genomics, transcriptomics, proteomics, and metabolomics technologies; 2) describe the advantages and challenges associated with these approaches compared to traditional methodologies, particularly from the perspective of cross-species extrapolation within human and environmental toxicology; and 3) identify solutions that will facilitate the incorporation of these technologies into environmental toxicology.


Original languageEnglish
Title of host publicationGenomic Approaches for Cross-Species Extrapolation in Toxicology
Publication statusPublished - 1 Jan 2007