Obesity, high-sensitive C-reactive protein and snoring in older Chinese: the Guangzhou Biobank Cohort Study

Research output: Contribution to journalArticle

Authors

  • XQ Lao
  • Chao Jiang
  • Wei Zhang
  • T Lam

Colleges, School and Institutes

Abstract

BACKGROUND: abitual snoring and elevated high-sensitive C-reactive protein (HsCRP) have both been associated with increased risk of cardiovascular disease. However, snoring and HsCRP are elevated in obese states which may thus be the primary determinant of both. We therefore investigated whether snoring may mediate the increased vascular risk directly through increased inflammation as indicated by HsCRP levels or if other determinants predominated in a large older Chinese population. METHODS: A total of 2508 males and 5709 females aged 50-85 years received a medical check-up including measurement of blood pressure, obesity indices, fasting total, LDL-, HDL-cholesterol, triglycerides, glucose and HsCRP. Information on self-reported snoring status was collected by standardized interview. RESULTS: The age-adjusted geometric mean HsCRP concentrations increased significantly with higher snoring frequency in both genders (linear trend, p=0.02 for men and p

Details

Original languageEnglish
Pages (from-to)1750-6
Number of pages7
JournalRespiratory Medicine
Volume104
Issue number11
Publication statusPublished - 1 Nov 2010

Keywords

  • Obesity, Snoring, Chinese, High-sensitive C-reactive protein