Novel polystyrene sulfonate–silica microspheres as a carrier of a water soluble inorganic salt (KCl) for its sustained release, via a dual-release mechanism

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@article{190f1a292d4a4b3b938f35885c24441d,
title = "Novel polystyrene sulfonate–silica microspheres as a carrier of a water soluble inorganic salt (KCl) for its sustained release, via a dual-release mechanism",
abstract = "Herein we describe a novel type of organic–inorganic composite solid microsphere, comprised of polystyrene sulfonate and silica (PSS–SiO2), which has been synthesised from polystyrene sulfonic acid and tetraethyl orthosilicate. The microsphere can (i) encapsulate a low molar mass (<100 Da) inorganic salt (KCl), and (ii) provide sustained release (>48 hours) of the salt from the microspheres to an aqueous environment, which has hitherto not been possible. We propose a novel dual-release mechanism of the salt from the microspheres, which leads to the sustained release, and therefore has potential applicability for the controlled and prolonged release of other actives.",
author = "Cong Sui and Jon Preece and Zhibing Zhang",
year = "2017",
month = jan,
day = "3",
doi = "10.1039/C6RA25488H",
language = "English",
volume = "7",
pages = "478--481",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "1",

}

RIS

TY - JOUR

T1 - Novel polystyrene sulfonate–silica microspheres as a carrier of a water soluble inorganic salt (KCl) for its sustained release, via a dual-release mechanism

AU - Sui, Cong

AU - Preece, Jon

AU - Zhang, Zhibing

PY - 2017/1/3

Y1 - 2017/1/3

N2 - Herein we describe a novel type of organic–inorganic composite solid microsphere, comprised of polystyrene sulfonate and silica (PSS–SiO2), which has been synthesised from polystyrene sulfonic acid and tetraethyl orthosilicate. The microsphere can (i) encapsulate a low molar mass (<100 Da) inorganic salt (KCl), and (ii) provide sustained release (>48 hours) of the salt from the microspheres to an aqueous environment, which has hitherto not been possible. We propose a novel dual-release mechanism of the salt from the microspheres, which leads to the sustained release, and therefore has potential applicability for the controlled and prolonged release of other actives.

AB - Herein we describe a novel type of organic–inorganic composite solid microsphere, comprised of polystyrene sulfonate and silica (PSS–SiO2), which has been synthesised from polystyrene sulfonic acid and tetraethyl orthosilicate. The microsphere can (i) encapsulate a low molar mass (<100 Da) inorganic salt (KCl), and (ii) provide sustained release (>48 hours) of the salt from the microspheres to an aqueous environment, which has hitherto not been possible. We propose a novel dual-release mechanism of the salt from the microspheres, which leads to the sustained release, and therefore has potential applicability for the controlled and prolonged release of other actives.

U2 - 10.1039/C6RA25488H

DO - 10.1039/C6RA25488H

M3 - Article

VL - 7

SP - 478

EP - 481

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 1

ER -