Novel polystyrene sulfonate–silica microspheres as a carrier of a water soluble inorganic salt (KCl) for its sustained release, via a dual-release mechanism

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Colleges, School and Institutes

Abstract

Herein we describe a novel type of organic–inorganic composite solid microsphere, comprised of polystyrene sulfonate and silica (PSS–SiO2), which has been synthesised from polystyrene sulfonic acid and tetraethyl orthosilicate. The microsphere can (i) encapsulate a low molar mass (<100 Da) inorganic salt (KCl), and (ii) provide sustained release (>48 hours) of the salt from the microspheres to an aqueous environment, which has hitherto not been possible. We propose a novel dual-release mechanism of the salt from the microspheres, which leads to the sustained release, and therefore has potential applicability for the controlled and prolonged release of other actives.

Details

Original languageEnglish
Pages (from-to)478-481
Number of pages4
JournalRSC Advances
Volume7
Issue number1
Publication statusPublished - 3 Jan 2017