New weapons in the Cryptococcus infection toolkit

Research output: Contribution to journalArticlepeer-review

Colleges, School and Institutes

Abstract

The global burden of fungal infections is unacceptably high. The human fungal pathogen Cryptococcus neoformans causes cryptococcosis and accounts for a significant proportion of this burden. Cryptococci undergo a number of elaborate interactions with their hosts, including survival and proliferation within phagocytes as well as dissemination to the central nervous system and other tissues. In this review we highlight a number of exciting recent advances in the field of cryptococcal biology. In particular we discuss new insights into cryptococcal morphology and its impact on virulence, as well as describing novel findings revealing how cryptoccoci may 'talk' to each other.

Details

Original languageEnglish
Pages (from-to)67-74
Number of pages8
JournalCurrent Opinion in Microbiology
Volume34
Early online date11 Aug 2016
Publication statusPublished - Dec 2016