Abstract
Optical coherence tomography (OCT) imaging plays an important role in clinical diagnosis and monitoring of diseases of the human retina. Automated analysis of optical coherence tomography images is a challenging task as the images are inherently noisy. In this paper, a novel variational image decomposition model is proposed to decompose an OCT image into three components: the first component is the original image but with the noise completely removed; the second contains the set of edges representing the retinal layer boundaries present in the image; and the third is an image of noise, or in image decomposition terms, the texture, or oscillatory patterns of the original image. In addition, a fast Fourier transform based split Bregman algorithm is developed to improve computational efficiency of solving the proposed model. Extensive experiments are conducted on both synthesised and real OCT images to demonstrate that the proposed model outperforms the state-of-the-art speckle noise reduction methods and leads to accurate retinal layer segmentation.
Original language | English |
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Pages (from-to) | 8901-8922 |
Number of pages | 22 |
Journal | Physics in Medicine and Biology |
Volume | 60 |
Issue number | 22 |
DOIs | |
Publication status | Published - 4 Nov 2015 |
Keywords
- fast Fourier transform
- image decomposition
- image segmentation
- noise removal
- Optical coherence tomography
- split Bregman algorithm
- variational methods
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging