Abstract
Atrial fibrillation (AF) confers an increased risk of ischemic stroke or thromboembolism that is reduced by long-term oral anticoagulant therapy. Until recently, the latter has typically been one from the vitamin K antagonist (VKA) class of drugs. Although highly effective, VKAs have limitations, and their use is challenging for both patients and clinicians. A new generation of oral anticoagulant drugs is emerging, including several drugs that appear to be viable alternatives to VKAs in AF patients.
Original language | English |
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Pages (from-to) | 502-506 |
Number of pages | 5 |
Journal | Clinical Pharmocology and Therapeutics |
Volume | 90 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Oct 2011 |