Neural communication patterns underlying conflict detection, resolution, and adaptation

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Neural communication patterns underlying conflict detection, resolution, and adaptation. / Oehrn, Carina R.; Hanslmayr, Simon; Fell, Juergen; Deuker, Lorena; Kremers, Nico A.; Do Lam, Anne T.; Elger, Christian E.; Axmacher, Nikolai.

In: Journal of Neuroscience, Vol. 34, No. 31, 01.01.2014, p. 10438-10452.

Research output: Contribution to journalArticle

Harvard

Oehrn, CR, Hanslmayr, S, Fell, J, Deuker, L, Kremers, NA, Do Lam, AT, Elger, CE & Axmacher, N 2014, 'Neural communication patterns underlying conflict detection, resolution, and adaptation', Journal of Neuroscience, vol. 34, no. 31, pp. 10438-10452. https://doi.org/10.1523/JNEUROSCI.3099-13.2014

APA

Oehrn, C. R., Hanslmayr, S., Fell, J., Deuker, L., Kremers, N. A., Do Lam, A. T., Elger, C. E., & Axmacher, N. (2014). Neural communication patterns underlying conflict detection, resolution, and adaptation. Journal of Neuroscience, 34(31), 10438-10452. https://doi.org/10.1523/JNEUROSCI.3099-13.2014

Vancouver

Author

Oehrn, Carina R. ; Hanslmayr, Simon ; Fell, Juergen ; Deuker, Lorena ; Kremers, Nico A. ; Do Lam, Anne T. ; Elger, Christian E. ; Axmacher, Nikolai. / Neural communication patterns underlying conflict detection, resolution, and adaptation. In: Journal of Neuroscience. 2014 ; Vol. 34, No. 31. pp. 10438-10452.

Bibtex

@article{c061b2c831594fb38e7ebbf5f3ef8f90,
title = "Neural communication patterns underlying conflict detection, resolution, and adaptation",
abstract = "In an ever-changing environment, selecting appropriate responses in conflicting situations is essential for biological survival and social success and requires cognitive control, which is mediated by dorsomedial prefrontal cortex (DMPFC) and dorsolateral prefrontal cortex (DLPFC). How these brain regions communicate during conflict processing (detection, resolution, and adaptation), however, is still unknown. The Stroop task provides a well-established paradigm to investigate the cognitive mechanisms mediating such response conflict. Here, we explore the oscillatory patterns within and between the DMPFC and DLPFC in human epilepsy patients with intracranial EEG electrodes during an auditory Stroop experiment. Data from the DLPFC were obtained from 12 patients. Thereof four patients had additional DMPFC electrodes available for interaction analyses. Our results show that an early θ (4-8 Hz) modulated enhancement of DLPFC γ-band (30-100 Hz) activity constituted a prerequisite for later successful conflict processing. Subsequent conflict detection was reflected in a DMPFC θ power increase that causally entrained DLPFC θ activity (DMPFC to DLPFC). Conflict resolution was thereafter completed by coupling of DLPFC γ power to DMPFC θ oscillations. Finally, conflict adaptation was related to increased postresponse DLPFC γ-band activity and to θ coupling in the reverse direction (DLPFC to DMPFC). These results draw a detailed picture on how two regions in the prefrontal cortex communicate to resolve cognitive conflicts. In conclusion, our data show that conflict detection, control, and adaptation are supported by a sequence of processes that use the interplay of θ and γ oscillations within and between DMPFC and DLPFC.",
keywords = "Dorsolateral prefrontal cortex, Dorsomedial prefrontal cortex, Oscillations, Stroop, γ, θ",
author = "Oehrn, {Carina R.} and Simon Hanslmayr and Juergen Fell and Lorena Deuker and Kremers, {Nico A.} and {Do Lam}, {Anne T.} and Elger, {Christian E.} and Nikolai Axmacher",
year = "2014",
month = jan,
day = "1",
doi = "10.1523/JNEUROSCI.3099-13.2014",
language = "English",
volume = "34",
pages = "10438--10452",
journal = "The Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "31",

}

RIS

TY - JOUR

T1 - Neural communication patterns underlying conflict detection, resolution, and adaptation

AU - Oehrn, Carina R.

AU - Hanslmayr, Simon

AU - Fell, Juergen

AU - Deuker, Lorena

AU - Kremers, Nico A.

AU - Do Lam, Anne T.

AU - Elger, Christian E.

AU - Axmacher, Nikolai

PY - 2014/1/1

Y1 - 2014/1/1

N2 - In an ever-changing environment, selecting appropriate responses in conflicting situations is essential for biological survival and social success and requires cognitive control, which is mediated by dorsomedial prefrontal cortex (DMPFC) and dorsolateral prefrontal cortex (DLPFC). How these brain regions communicate during conflict processing (detection, resolution, and adaptation), however, is still unknown. The Stroop task provides a well-established paradigm to investigate the cognitive mechanisms mediating such response conflict. Here, we explore the oscillatory patterns within and between the DMPFC and DLPFC in human epilepsy patients with intracranial EEG electrodes during an auditory Stroop experiment. Data from the DLPFC were obtained from 12 patients. Thereof four patients had additional DMPFC electrodes available for interaction analyses. Our results show that an early θ (4-8 Hz) modulated enhancement of DLPFC γ-band (30-100 Hz) activity constituted a prerequisite for later successful conflict processing. Subsequent conflict detection was reflected in a DMPFC θ power increase that causally entrained DLPFC θ activity (DMPFC to DLPFC). Conflict resolution was thereafter completed by coupling of DLPFC γ power to DMPFC θ oscillations. Finally, conflict adaptation was related to increased postresponse DLPFC γ-band activity and to θ coupling in the reverse direction (DLPFC to DMPFC). These results draw a detailed picture on how two regions in the prefrontal cortex communicate to resolve cognitive conflicts. In conclusion, our data show that conflict detection, control, and adaptation are supported by a sequence of processes that use the interplay of θ and γ oscillations within and between DMPFC and DLPFC.

AB - In an ever-changing environment, selecting appropriate responses in conflicting situations is essential for biological survival and social success and requires cognitive control, which is mediated by dorsomedial prefrontal cortex (DMPFC) and dorsolateral prefrontal cortex (DLPFC). How these brain regions communicate during conflict processing (detection, resolution, and adaptation), however, is still unknown. The Stroop task provides a well-established paradigm to investigate the cognitive mechanisms mediating such response conflict. Here, we explore the oscillatory patterns within and between the DMPFC and DLPFC in human epilepsy patients with intracranial EEG electrodes during an auditory Stroop experiment. Data from the DLPFC were obtained from 12 patients. Thereof four patients had additional DMPFC electrodes available for interaction analyses. Our results show that an early θ (4-8 Hz) modulated enhancement of DLPFC γ-band (30-100 Hz) activity constituted a prerequisite for later successful conflict processing. Subsequent conflict detection was reflected in a DMPFC θ power increase that causally entrained DLPFC θ activity (DMPFC to DLPFC). Conflict resolution was thereafter completed by coupling of DLPFC γ power to DMPFC θ oscillations. Finally, conflict adaptation was related to increased postresponse DLPFC γ-band activity and to θ coupling in the reverse direction (DLPFC to DMPFC). These results draw a detailed picture on how two regions in the prefrontal cortex communicate to resolve cognitive conflicts. In conclusion, our data show that conflict detection, control, and adaptation are supported by a sequence of processes that use the interplay of θ and γ oscillations within and between DMPFC and DLPFC.

KW - Dorsolateral prefrontal cortex

KW - Dorsomedial prefrontal cortex

KW - Oscillations

KW - Stroop

KW - γ

KW - θ

UR - http://www.scopus.com/inward/record.url?scp=84905020678&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.3099-13.2014

DO - 10.1523/JNEUROSCI.3099-13.2014

M3 - Article

C2 - 25080602

AN - SCOPUS:84905020678

VL - 34

SP - 10438

EP - 10452

JO - The Journal of Neuroscience

JF - The Journal of Neuroscience

SN - 0270-6474

IS - 31

ER -