Nasopharyngeal carcinoma and the EBV-specific T cell response: Prospects for immunotherapy
Research output: Contribution to journal › Article
Colleges, School and Institutes
T cells specific for Epstein-Barr virus (EBV) can effectively target the virus-transformed B lymphoproliferative lesions that arise in immunosuppressed transplant patients. This review explores the possibility of developing similar T cell-based strategies to treat an EBV-positive epithelial tumour, nasopharyngeal carcinoma (NPC), which arises in relatively immunocompetent individuals and where EBV antigen expression in the tumour is more limited.
|Number of pages||9|
|Journal||Seminars in Cancer Biology|
|Publication status||Published - 1 Dec 2002|