Multispectral, non-contact diffuse optical tomography of healthy human finger joints

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Multispectral, non-contact diffuse optical tomography of healthy human finger joints. / Lighter, Daniel; Hughes, James; Styles, Iain; Filer, Andrew; Dehghani, Hamid.

In: Biomedical Optics Express, Vol. 9, No. 4, 01.04.2018, p. 1445-1460.

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@article{5da7d97dc61c40c2b5b557f07530b4f7,
title = "Multispectral, non-contact diffuse optical tomography of healthy human finger joints",
abstract = "Rheumatoid arthritis (RA) is an inflammatory joint disease often affecting the hands, which if untreated causes disability. Diffuse optical tomography (DOT) provides information about underlying functional properties of biological tissue. To detect pathophysiological changes in inflamed RA joints, a good understanding of baseline values for healthy subjects is first required. Finger joints from healthy subjects were imaged using a non-contact, multispectral,continuous wave DOT system, recovering physiological parameters of oxygen saturation, total haemoglobin, water concentration and scatter amplitude. Reconstructed values across the cohort demonstrated good consistency between finger joints from the same participant, with greater variation seen between subjects.",
author = "Daniel Lighter and James Hughes and Iain Styles and Andrew Filer and Hamid Dehghani",
year = "2018",
month = "4",
day = "1",
doi = "10.1364/BOE.9.001445",
language = "English",
volume = "9",
pages = "1445--1460",
journal = "Biomedical Optics Express",
issn = "2156-7085",
publisher = "Optical Society of America",
number = "4",

}

RIS

TY - JOUR

T1 - Multispectral, non-contact diffuse optical tomography of healthy human finger joints

AU - Lighter, Daniel

AU - Hughes, James

AU - Styles, Iain

AU - Filer, Andrew

AU - Dehghani, Hamid

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Rheumatoid arthritis (RA) is an inflammatory joint disease often affecting the hands, which if untreated causes disability. Diffuse optical tomography (DOT) provides information about underlying functional properties of biological tissue. To detect pathophysiological changes in inflamed RA joints, a good understanding of baseline values for healthy subjects is first required. Finger joints from healthy subjects were imaged using a non-contact, multispectral,continuous wave DOT system, recovering physiological parameters of oxygen saturation, total haemoglobin, water concentration and scatter amplitude. Reconstructed values across the cohort demonstrated good consistency between finger joints from the same participant, with greater variation seen between subjects.

AB - Rheumatoid arthritis (RA) is an inflammatory joint disease often affecting the hands, which if untreated causes disability. Diffuse optical tomography (DOT) provides information about underlying functional properties of biological tissue. To detect pathophysiological changes in inflamed RA joints, a good understanding of baseline values for healthy subjects is first required. Finger joints from healthy subjects were imaged using a non-contact, multispectral,continuous wave DOT system, recovering physiological parameters of oxygen saturation, total haemoglobin, water concentration and scatter amplitude. Reconstructed values across the cohort demonstrated good consistency between finger joints from the same participant, with greater variation seen between subjects.

U2 - 10.1364/BOE.9.001445

DO - 10.1364/BOE.9.001445

M3 - Article

VL - 9

SP - 1445

EP - 1460

JO - Biomedical Optics Express

JF - Biomedical Optics Express

SN - 2156-7085

IS - 4

ER -