More pieces in the promoter jigsaw: recognition of -10 regions by alternative sigma factors.

Research output: Contribution to journalArticle


Colleges, School and Institutes


Two papers in this issue of Molecular Microbiology from Carol Gross and colleagues describe experiments that investigate how two alternative Escherichia coli sigma proteins recognize target promoter -10 regions. A combination of genetics, biochemistry and bioinformatics is used to show that determinants in two adjacent domains of the sigma proteins contact discrete sequence elements in the -10 regions.


Original languageEnglish
Pages (from-to)809-11
Number of pages3
JournalMolecular Microbiology
Issue number4
Publication statusPublished - 1 May 2009