Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC

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Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC. / Materić, Dušan; Lanza, Matteo; Sulzer, Philipp; Herbig, Jens; Bruhn, Dan; Turner, Claire; Mason, Nigel; Gauci, Vincent.

In: Analytical and Bioanalytical Chemistry, 01.10.2015.

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Materić, Dušan ; Lanza, Matteo ; Sulzer, Philipp ; Herbig, Jens ; Bruhn, Dan ; Turner, Claire ; Mason, Nigel ; Gauci, Vincent. / Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC. In: Analytical and Bioanalytical Chemistry. 2015.

Bibtex

@article{91883c3253bf41269eb5a632688ff159,
title = "Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC",
abstract = "Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a well-established technique for real-time VOCs (Volatile Organic Compounds) analysis. Although, it is extremely sensitive (with sensitivities of up to 4500 cps/ppbv, limits of the detection <1 pptv and the response times of approximately 100 ms) the selectivity of PTR-MS is still somewhat limited, as isomers cannot be separated. Recently, selectivity-enhancing measures, such as manipulation of drift tube parameters (reduced electric field strength) and using primary ions other than H3O+, such as NO+ and O2+ have been introduced. However, monoterpenes, which belong to the most important plant VOCs, still cannot be distinguished so that more traditional technologies, such as gas chromatography mass spectrometry (GC-MS), have to be utilized. GC-MS is very time consuming (up to 1 h) and cannot be used for real-time analysis. Here we introduce a sensitive, near real-time method for plant monoterpene research: PTR-MS coupled with fastGC. We successfully separated and identified six of the most abundant monoterpenes in plant studies (α- and β-pinenes, limonene, 3-carene, camphene, and myrcene) in less than 80 s, using both standards and conifer branch enclosures (Norway spruce, Scots pine and Black pine). Five monoterpenes usually present in Norway spruce samples with a high abundance were separated even when the compound concentrations were diluted to 20 ppbv. Thus, fastGC-PTR-ToF-MS was shown to be an adequate one-instrument solution for plant monoterpene research.",
author = "Du{\v s}an Materi{\'c} and Matteo Lanza and Philipp Sulzer and Jens Herbig and Dan Bruhn and Claire Turner and Nigel Mason and Vincent Gauci",
year = "2015",
month = oct,
day = "1",
doi = "10.1007/s00216-015-8942-5",
language = "Undefined/Unknown",
journal = "Analytical and Bioanalytical Chemistry",
issn = "1618-2642",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC

AU - Materić, Dušan

AU - Lanza, Matteo

AU - Sulzer, Philipp

AU - Herbig, Jens

AU - Bruhn, Dan

AU - Turner, Claire

AU - Mason, Nigel

AU - Gauci, Vincent

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a well-established technique for real-time VOCs (Volatile Organic Compounds) analysis. Although, it is extremely sensitive (with sensitivities of up to 4500 cps/ppbv, limits of the detection <1 pptv and the response times of approximately 100 ms) the selectivity of PTR-MS is still somewhat limited, as isomers cannot be separated. Recently, selectivity-enhancing measures, such as manipulation of drift tube parameters (reduced electric field strength) and using primary ions other than H3O+, such as NO+ and O2+ have been introduced. However, monoterpenes, which belong to the most important plant VOCs, still cannot be distinguished so that more traditional technologies, such as gas chromatography mass spectrometry (GC-MS), have to be utilized. GC-MS is very time consuming (up to 1 h) and cannot be used for real-time analysis. Here we introduce a sensitive, near real-time method for plant monoterpene research: PTR-MS coupled with fastGC. We successfully separated and identified six of the most abundant monoterpenes in plant studies (α- and β-pinenes, limonene, 3-carene, camphene, and myrcene) in less than 80 s, using both standards and conifer branch enclosures (Norway spruce, Scots pine and Black pine). Five monoterpenes usually present in Norway spruce samples with a high abundance were separated even when the compound concentrations were diluted to 20 ppbv. Thus, fastGC-PTR-ToF-MS was shown to be an adequate one-instrument solution for plant monoterpene research.

AB - Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a well-established technique for real-time VOCs (Volatile Organic Compounds) analysis. Although, it is extremely sensitive (with sensitivities of up to 4500 cps/ppbv, limits of the detection <1 pptv and the response times of approximately 100 ms) the selectivity of PTR-MS is still somewhat limited, as isomers cannot be separated. Recently, selectivity-enhancing measures, such as manipulation of drift tube parameters (reduced electric field strength) and using primary ions other than H3O+, such as NO+ and O2+ have been introduced. However, monoterpenes, which belong to the most important plant VOCs, still cannot be distinguished so that more traditional technologies, such as gas chromatography mass spectrometry (GC-MS), have to be utilized. GC-MS is very time consuming (up to 1 h) and cannot be used for real-time analysis. Here we introduce a sensitive, near real-time method for plant monoterpene research: PTR-MS coupled with fastGC. We successfully separated and identified six of the most abundant monoterpenes in plant studies (α- and β-pinenes, limonene, 3-carene, camphene, and myrcene) in less than 80 s, using both standards and conifer branch enclosures (Norway spruce, Scots pine and Black pine). Five monoterpenes usually present in Norway spruce samples with a high abundance were separated even when the compound concentrations were diluted to 20 ppbv. Thus, fastGC-PTR-ToF-MS was shown to be an adequate one-instrument solution for plant monoterpene research.

U2 - 10.1007/s00216-015-8942-5

DO - 10.1007/s00216-015-8942-5

M3 - Article

JO - Analytical and Bioanalytical Chemistry

JF - Analytical and Bioanalytical Chemistry

SN - 1618-2642

ER -