Model-based Correction of Segmentation Errors in Digitised Histological Images
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Model-based Correction of Segmentation Errors in Digitised Histological Images. / Randell, David; Galton, Antony; Fouad, Shereen; Mehanna, Hesham; Landini, Gabriel.
Medical image understanding and analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings. Springer, 2017. p. 718-730 (Communications in computer and information science; Vol. 723).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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TY - GEN
T1 - Model-based Correction of Segmentation Errors in Digitised Histological Images
AU - Randell, David
AU - Galton, Antony
AU - Fouad, Shereen
AU - Mehanna, Hesham
AU - Landini, Gabriel
PY - 2017
Y1 - 2017
N2 - This paper describes an application of model-based methods for the algorithmic correction of segmentation errors in digitised histo- logical images. This is a real-world application where qualitative spatial reasoning and constraint-satisfaction programming methods have been integrated with classical image processing methods to develop context- based histological imaging algorithms. The context here arises from: (i) making an ontological stand whereby regions rather than pixels in digi- tised images are deemed to be the main carriers of histological content, and (ii) highlighting the importance of and explicitly modelling topo- logical (and in particular relational) information encoded in digitised histological images. The topological analysis and representational frame- work used is provided by the spatial logic Discrete Meterotopology. We use this to augment classical Mathematical Morphology pixel and region- based operations by explicitly encoding sets of binary relations on pairs of regions such as contact, overlap and the part-whole relation. These mereotopological relations are used both to model the domain and to guide resegmentation algorithms so that our interpreted images conform to the requirements for a valid histological model.
AB - This paper describes an application of model-based methods for the algorithmic correction of segmentation errors in digitised histo- logical images. This is a real-world application where qualitative spatial reasoning and constraint-satisfaction programming methods have been integrated with classical image processing methods to develop context- based histological imaging algorithms. The context here arises from: (i) making an ontological stand whereby regions rather than pixels in digi- tised images are deemed to be the main carriers of histological content, and (ii) highlighting the importance of and explicitly modelling topo- logical (and in particular relational) information encoded in digitised histological images. The topological analysis and representational frame- work used is provided by the spatial logic Discrete Meterotopology. We use this to augment classical Mathematical Morphology pixel and region- based operations by explicitly encoding sets of binary relations on pairs of regions such as contact, overlap and the part-whole relation. These mereotopological relations are used both to model the domain and to guide resegmentation algorithms so that our interpreted images conform to the requirements for a valid histological model.
KW - Histological Image Processing
KW - Mereotopology
KW - Graph Theory
U2 - 10.1007/978-3-319-60964-5_63
DO - 10.1007/978-3-319-60964-5_63
M3 - Conference contribution
SN - 978-3-319-60963-8
T3 - Communications in computer and information science
SP - 718
EP - 730
BT - Medical image understanding and analysis
PB - Springer
T2 - Medical Image Understanding and Analysis (MIUA) 2017
Y2 - 11 July 2017 through 13 July 2017
ER -