Mild bleeding disorders: what every clinician should know

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Mild bleeding disorders: what every clinician should know. / Nicolson, Phillip; Hussein, Hayder; Fordwor, Katrina; Lowe, Gillian.

In: British journal of hospital medicine, Vol. 78, No. 12, 02.12.2017, p. 684-710.

Research output: Contribution to journalArticle

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Nicolson, Phillip ; Hussein, Hayder ; Fordwor, Katrina ; Lowe, Gillian. / Mild bleeding disorders: what every clinician should know. In: British journal of hospital medicine. 2017 ; Vol. 78, No. 12. pp. 684-710.

Bibtex

@article{c61681a48c224129bdfaa54d80884061,
title = "Mild bleeding disorders:: what every clinician should know",
abstract = "Patients with mild bleeding disorders are under-recognized and frequently present to general physicians. The underlying reasons for bleeding are multifactorial. There is little evidence to guide diagnostic and management decision making in patients with mild bleeding disorders.This article outlines different types of mild bleeding disorders, with a particular focus on bleeding associated with low levels of von Willebrand factor and mild platelet defects. It gives practical, evidence-based advice on the investigation and management of patients with a suspected or known mild bleeding disorder, considering the scenarios of an acute bleed, stable outpatient, peri-surgical management and thrombosis.Patients with a mild bleeding disorder have variable bleeding because of the interplay of genetic and environmental factors. The clinical history remains of utmost importance in their general management. Liaison with a specialist centre, multidisciplinary assessment and a careful judgement of the balance of risk in each individual circumstance is required to safely manage these patients",
keywords = "bleeding, coagulation, haemostasis, von Willebrand's factor, platelets, mild bleeding disorders",
author = "Phillip Nicolson and Hayder Hussein and Katrina Fordwor and Gillian Lowe",
year = "2017",
month = dec,
day = "2",
doi = "10.12968/hmed.2017.78.12.684",
language = "English",
volume = "78",
pages = "684--710",
journal = "British journal of hospital medicine",
issn = "1750-8460",
publisher = "Mark Allen Healthcare",
number = "12",

}

RIS

TY - JOUR

T1 - Mild bleeding disorders:

T2 - what every clinician should know

AU - Nicolson, Phillip

AU - Hussein, Hayder

AU - Fordwor, Katrina

AU - Lowe, Gillian

PY - 2017/12/2

Y1 - 2017/12/2

N2 - Patients with mild bleeding disorders are under-recognized and frequently present to general physicians. The underlying reasons for bleeding are multifactorial. There is little evidence to guide diagnostic and management decision making in patients with mild bleeding disorders.This article outlines different types of mild bleeding disorders, with a particular focus on bleeding associated with low levels of von Willebrand factor and mild platelet defects. It gives practical, evidence-based advice on the investigation and management of patients with a suspected or known mild bleeding disorder, considering the scenarios of an acute bleed, stable outpatient, peri-surgical management and thrombosis.Patients with a mild bleeding disorder have variable bleeding because of the interplay of genetic and environmental factors. The clinical history remains of utmost importance in their general management. Liaison with a specialist centre, multidisciplinary assessment and a careful judgement of the balance of risk in each individual circumstance is required to safely manage these patients

AB - Patients with mild bleeding disorders are under-recognized and frequently present to general physicians. The underlying reasons for bleeding are multifactorial. There is little evidence to guide diagnostic and management decision making in patients with mild bleeding disorders.This article outlines different types of mild bleeding disorders, with a particular focus on bleeding associated with low levels of von Willebrand factor and mild platelet defects. It gives practical, evidence-based advice on the investigation and management of patients with a suspected or known mild bleeding disorder, considering the scenarios of an acute bleed, stable outpatient, peri-surgical management and thrombosis.Patients with a mild bleeding disorder have variable bleeding because of the interplay of genetic and environmental factors. The clinical history remains of utmost importance in their general management. Liaison with a specialist centre, multidisciplinary assessment and a careful judgement of the balance of risk in each individual circumstance is required to safely manage these patients

KW - bleeding

KW - coagulation

KW - haemostasis

KW - von Willebrand's factor

KW - platelets

KW - mild bleeding disorders

U2 - 10.12968/hmed.2017.78.12.684

DO - 10.12968/hmed.2017.78.12.684

M3 - Article

VL - 78

SP - 684

EP - 710

JO - British journal of hospital medicine

JF - British journal of hospital medicine

SN - 1750-8460

IS - 12

ER -