Mild bleeding disorders: what every clinician should know

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

External organisations

  • Department of Medicine, Chelsea and Westminster Hospital
  • Department of Clinical Haematology, Queen Elizabeth Hospital

Abstract

Patients with mild bleeding disorders are under-recognized and frequently present to general physicians. The underlying reasons for bleeding are multifactorial. There is little evidence to guide diagnostic and management decision making in patients with mild bleeding disorders.

This article outlines different types of mild bleeding disorders, with a particular focus on bleeding associated with low levels of von Willebrand factor and mild platelet defects. It gives practical, evidence-based advice on the investigation and management of patients with a suspected or known mild bleeding disorder, considering the scenarios of an acute bleed, stable outpatient, peri-surgical management and thrombosis.

Patients with a mild bleeding disorder have variable bleeding because of the interplay of genetic and environmental factors. The clinical history remains of utmost importance in their general management. Liaison with a specialist centre, multidisciplinary assessment and a careful judgement of the balance of risk in each individual circumstance is required to safely manage these patients

Details

Original languageEnglish
Pages (from-to)684-710
JournalBritish journal of hospital medicine
Volume78
Issue number12
Publication statusPublished - 2 Dec 2017

Keywords

  • bleeding, coagulation, haemostasis, von Willebrand's factor, platelets, mild bleeding disorders