Microwave-to-terahertz dielectric resonators for liquid sensing in microfluidic systems
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Microwave-to-terahertz dielectric resonators for liquid sensing in microfluidic systems. / Klein, N.; Watts, C.; Hanham, S. M.; Otter, W. J.; Ahmad, M. M.; Lucyszyn, S.
Terahertz Emitters, Receivers, and Applications VII. ed. / Manijeh Razeghi; Alexei N. Baranov; John M. Zavada; Dimitris Pavlidis. Society of Photo-Optical Instrumentation Engineers, 2016. 99340F (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 9934).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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TY - GEN
T1 - Microwave-to-terahertz dielectric resonators for liquid sensing in microfluidic systems
AU - Klein, N.
AU - Watts, C.
AU - Hanham, S. M.
AU - Otter, W. J.
AU - Ahmad, M. M.
AU - Lucyszyn, S.
PY - 2016/9/26
Y1 - 2016/9/26
N2 - The microwave-to-terahertz frequency range offers unique opportunities for the sensing of liquids based on the degree of molecular orientational and electronic polarization, Debye relaxation due to intermolecular forces between (semi-)polar molecules and collective vibrational modes within complex molecules. Methods for the fast dielectric characterization of (sub-)nanolitre volumes of mostly aqueous liquids and biological cell suspensions are discussed, with emphasis on labon-chip approaches aimed towards single-cell detection and label-free flow cytometry at microwave-to-terahertz frequencies. Among the most promising approaches, photonic crystal defect cavities made from high-resistivity silicon are compared with metallic split-ring resonant systems and high quality factor (Q-factor) whispering gallery-type resonances in dielectric resonators. Applications range from accurate haemoglobin measurements on nanolitre samples to label-free detection of circulating tumor cells.
AB - The microwave-to-terahertz frequency range offers unique opportunities for the sensing of liquids based on the degree of molecular orientational and electronic polarization, Debye relaxation due to intermolecular forces between (semi-)polar molecules and collective vibrational modes within complex molecules. Methods for the fast dielectric characterization of (sub-)nanolitre volumes of mostly aqueous liquids and biological cell suspensions are discussed, with emphasis on labon-chip approaches aimed towards single-cell detection and label-free flow cytometry at microwave-to-terahertz frequencies. Among the most promising approaches, photonic crystal defect cavities made from high-resistivity silicon are compared with metallic split-ring resonant systems and high quality factor (Q-factor) whispering gallery-type resonances in dielectric resonators. Applications range from accurate haemoglobin measurements on nanolitre samples to label-free detection of circulating tumor cells.
KW - dielectric resonators
KW - label free cancer cell detection
KW - microwave and terahertz liquid characterization
KW - photonic crystal resonators
UR - http://www.scopus.com/inward/record.url?scp=85006983721&partnerID=8YFLogxK
U2 - 10.1117/12.2238545
DO - 10.1117/12.2238545
M3 - Conference contribution
AN - SCOPUS:85006983721
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Terahertz Emitters, Receivers, and Applications VII
A2 - Razeghi, Manijeh
A2 - Baranov, Alexei N.
A2 - Zavada, John M.
A2 - Pavlidis, Dimitris
PB - Society of Photo-Optical Instrumentation Engineers
T2 - Terahertz Emitters, Receivers, and Applications VII
Y2 - 28 August 2016 through 31 August 2016
ER -