Microwave-to-terahertz dielectric resonators for liquid sensing in microfluidic systems
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Authors
Colleges, School and Institutes
External organisations
- Imperial College London
- Department of Materials
Abstract
The microwave-to-terahertz frequency range offers unique opportunities for the sensing of liquids based on the degree of molecular orientational and electronic polarization, Debye relaxation due to intermolecular forces between (semi-)polar molecules and collective vibrational modes within complex molecules. Methods for the fast dielectric characterization of (sub-)nanolitre volumes of mostly aqueous liquids and biological cell suspensions are discussed, with emphasis on labon-chip approaches aimed towards single-cell detection and label-free flow cytometry at microwave-to-terahertz frequencies. Among the most promising approaches, photonic crystal defect cavities made from high-resistivity silicon are compared with metallic split-ring resonant systems and high quality factor (Q-factor) whispering gallery-type resonances in dielectric resonators. Applications range from accurate haemoglobin measurements on nanolitre samples to label-free detection of circulating tumor cells.
Details
Original language | English |
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Title of host publication | Terahertz Emitters, Receivers, and Applications VII |
Editors | Manijeh Razeghi, Alexei N. Baranov, John M. Zavada, Dimitris Pavlidis |
Publication status | Published - 26 Sep 2016 |
Event | Terahertz Emitters, Receivers, and Applications VII - San Diego, United States Duration: 28 Aug 2016 → 31 Aug 2016 |
Publication series
Name | Proceedings of SPIE - The International Society for Optical Engineering |
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Volume | 9934 |
ISSN (Print) | 0277-786X |
ISSN (Electronic) | 1996-756X |
Conference
Conference | Terahertz Emitters, Receivers, and Applications VII |
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Country | United States |
City | San Diego |
Period | 28/08/16 → 31/08/16 |
Keywords
- dielectric resonators, label free cancer cell detection, microwave and terahertz liquid characterization, photonic crystal resonators