Metazoan DNA replication origins

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Metazoan DNA replication origins. / Ganier, Olivier ; Prorok, Paulina; Akerman, Ildem; Méchali, Marcel.

In: Current Opinion in Cell Biology, Vol. 58, 11.06.2019, p. 134-141.

Research output: Contribution to journalArticlepeer-review

Harvard

Ganier, O, Prorok, P, Akerman, I & Méchali, M 2019, 'Metazoan DNA replication origins', Current Opinion in Cell Biology, vol. 58, pp. 134-141.

APA

Ganier, O., Prorok, P., Akerman, I., & Méchali, M. (2019). Metazoan DNA replication origins. Current Opinion in Cell Biology, 58, 134-141.

Vancouver

Ganier O, Prorok P, Akerman I, Méchali M. Metazoan DNA replication origins. Current Opinion in Cell Biology. 2019 Jun 11;58:134-141.

Author

Ganier, Olivier ; Prorok, Paulina ; Akerman, Ildem ; Méchali, Marcel. / Metazoan DNA replication origins. In: Current Opinion in Cell Biology. 2019 ; Vol. 58. pp. 134-141.

Bibtex

@article{517469018d524accacd466c866b9f290,
title = "Metazoan DNA replication origins",
abstract = "DNA replication starts with the opening of DNA at sites called DNA replication origins. From the single sequence-specific DNA replication origin of the small Escherichia coli genome, up to thousands of origins that are necessary to replicate the large human genome, strict sequence specificity has been lost. Nevertheless, genome-wide analyses performed in the recent years, using different mapping methods, demonstrated that there are precise locations along the metazoan genome from which replication initiates. These sites contain relaxed sequence consensus and epigenetic features. There is flexibility in the choice of origins to be used during a given cell cycle, probably imposed by evolution and developmental constraints. Here, we will briefly describe their main features.",
author = "Olivier Ganier and Paulina Prorok and Ildem Akerman and Marcel M{\'e}chali",
year = "2019",
month = jun,
day = "11",
language = "English",
volume = "58",
pages = "134--141",
journal = "Current Opinion in Cell Biology",
issn = "0955-0674",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Metazoan DNA replication origins

AU - Ganier, Olivier

AU - Prorok, Paulina

AU - Akerman, Ildem

AU - Méchali, Marcel

PY - 2019/6/11

Y1 - 2019/6/11

N2 - DNA replication starts with the opening of DNA at sites called DNA replication origins. From the single sequence-specific DNA replication origin of the small Escherichia coli genome, up to thousands of origins that are necessary to replicate the large human genome, strict sequence specificity has been lost. Nevertheless, genome-wide analyses performed in the recent years, using different mapping methods, demonstrated that there are precise locations along the metazoan genome from which replication initiates. These sites contain relaxed sequence consensus and epigenetic features. There is flexibility in the choice of origins to be used during a given cell cycle, probably imposed by evolution and developmental constraints. Here, we will briefly describe their main features.

AB - DNA replication starts with the opening of DNA at sites called DNA replication origins. From the single sequence-specific DNA replication origin of the small Escherichia coli genome, up to thousands of origins that are necessary to replicate the large human genome, strict sequence specificity has been lost. Nevertheless, genome-wide analyses performed in the recent years, using different mapping methods, demonstrated that there are precise locations along the metazoan genome from which replication initiates. These sites contain relaxed sequence consensus and epigenetic features. There is flexibility in the choice of origins to be used during a given cell cycle, probably imposed by evolution and developmental constraints. Here, we will briefly describe their main features.

M3 - Article

VL - 58

SP - 134

EP - 141

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

SN - 0955-0674

ER -