Metalloproteinases in idiopathic pulmonary fibrosis.
Research output: Contribution to journal › Article
Colleges, School and Institutes
In this review, we outline the current state of knowledge about the balance between collagen production and degradation in idiopathic pulmonary fibrosis (IPF). The dysregulated action of metalloproteinases implicated in IPF may play a central role in the disease pathogenesis. Inhibiting metalloproteinases in IPF may therefore have therapeutic potential but our knowledge of their pathophysiological role is held back by limited animal models and the lack of specific inhibitors.
|Journal||The European respiratory journal|
|Publication status||Published - 23 Jun 2011|