Mesenchymal stem cells as endogenous regulators of inflammation

Research output: Chapter in Book/Report/Conference proceedingChapter

Standard

Mesenchymal stem cells as endogenous regulators of inflammation. / Munir, Hafsa; Ward, Lewis S.C.; McGettrick, Helen M.

Stromal Immunology. Springer, 2018. p. 73-98 (Advances in Experimental Medicine and Biology; Vol. 1060).

Research output: Chapter in Book/Report/Conference proceedingChapter

Harvard

Munir, H, Ward, LSC & McGettrick, HM 2018, Mesenchymal stem cells as endogenous regulators of inflammation. in Stromal Immunology. Advances in Experimental Medicine and Biology, vol. 1060, Springer, pp. 73-98. https://doi.org/10.1007/978-3-319-78127-3_5

APA

Munir, H., Ward, L. S. C., & McGettrick, H. M. (2018). Mesenchymal stem cells as endogenous regulators of inflammation. In Stromal Immunology (pp. 73-98). (Advances in Experimental Medicine and Biology; Vol. 1060). Springer. https://doi.org/10.1007/978-3-319-78127-3_5

Vancouver

Munir H, Ward LSC, McGettrick HM. Mesenchymal stem cells as endogenous regulators of inflammation. In Stromal Immunology. Springer. 2018. p. 73-98. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-319-78127-3_5

Author

Munir, Hafsa ; Ward, Lewis S.C. ; McGettrick, Helen M. / Mesenchymal stem cells as endogenous regulators of inflammation. Stromal Immunology. Springer, 2018. pp. 73-98 (Advances in Experimental Medicine and Biology).

Bibtex

@inbook{6be100422c9e4b46a37e16d47ced80f1,
title = "Mesenchymal stem cells as endogenous regulators of inflammation",
abstract = "This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC) during an inflammatory response. MSC are a heterogeneous population of multipotent cells that normally contribute towards tissue maintenance and repair but have garnered significant scientific interest for their potent immunomodulatory potential. It is through these physicochemical interactions that MSC are able to exert an anti-inflammatory response on neighbouring stromal and haematopoietic cells. However, the impact of the chronic inflammatory environment on MSC function remains to be determined. Understanding the relationship of MSC between resolution of inflammation and autoimmunity will both offer new insights in the use of MSC as a therapeutic, and also their involvement in the pathogenesis of inflammatory disorders.",
keywords = "Endothelial cells, Lymphocytes, Mesenchymal stem cells, Neutrophils",
author = "Hafsa Munir and Ward, {Lewis S.C.} and McGettrick, {Helen M.}",
year = "2018",
month = aug,
day = "29",
doi = "10.1007/978-3-319-78127-3_5",
language = "English",
isbn = "9783319781259",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "73--98",
booktitle = "Stromal Immunology",

}

RIS

TY - CHAP

T1 - Mesenchymal stem cells as endogenous regulators of inflammation

AU - Munir, Hafsa

AU - Ward, Lewis S.C.

AU - McGettrick, Helen M.

PY - 2018/8/29

Y1 - 2018/8/29

N2 - This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC) during an inflammatory response. MSC are a heterogeneous population of multipotent cells that normally contribute towards tissue maintenance and repair but have garnered significant scientific interest for their potent immunomodulatory potential. It is through these physicochemical interactions that MSC are able to exert an anti-inflammatory response on neighbouring stromal and haematopoietic cells. However, the impact of the chronic inflammatory environment on MSC function remains to be determined. Understanding the relationship of MSC between resolution of inflammation and autoimmunity will both offer new insights in the use of MSC as a therapeutic, and also their involvement in the pathogenesis of inflammatory disorders.

AB - This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC) during an inflammatory response. MSC are a heterogeneous population of multipotent cells that normally contribute towards tissue maintenance and repair but have garnered significant scientific interest for their potent immunomodulatory potential. It is through these physicochemical interactions that MSC are able to exert an anti-inflammatory response on neighbouring stromal and haematopoietic cells. However, the impact of the chronic inflammatory environment on MSC function remains to be determined. Understanding the relationship of MSC between resolution of inflammation and autoimmunity will both offer new insights in the use of MSC as a therapeutic, and also their involvement in the pathogenesis of inflammatory disorders.

KW - Endothelial cells

KW - Lymphocytes

KW - Mesenchymal stem cells

KW - Neutrophils

UR - http://www.scopus.com/inward/record.url?scp=85052681800&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-78127-3_5

DO - 10.1007/978-3-319-78127-3_5

M3 - Chapter

AN - SCOPUS:85052681800

SN - 9783319781259

T3 - Advances in Experimental Medicine and Biology

SP - 73

EP - 98

BT - Stromal Immunology

PB - Springer

ER -