Memory reconsolidation mediates the strengthening of memories by additional learning

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Colleges, School and Institutes


Memories are dynamic, rather than static, in nature. The reactivation of a memory through re-exposure to salient training stimuli results in its destabilization, necessitating a restabilization process known as reconsolidation, a disruption of which leads to amnesia. I found that one normal function of hippocampal memory reconsolidation in rats is to modify the strength of a contextual-fear memory as a result of further learning.


Original languageEnglish
Pages (from-to)1264-6
Number of pages3
JournalNature Neuroscience
Issue number11
Publication statusPublished - 1 Nov 2008