Medication review plus person-centred care: a feasibility study of a pharmacy-health psychology dual intervention to improve care for people living with dementia

Research output: Contribution to journalArticle


  • Ian Maidment
  • Niyah Campbell
  • Nichola Seare
  • Chris Fox
  • Steve Iliffe
  • Andrea Hilton
  • Graeme Brown
  • Nigel Barnes
  • Jane Wilcock
  • Emma Randle
  • Sarah Gillespie
  • Garry Barton
  • Rachel Shaw

Colleges, School and Institutes

External organisations

  • School of Life and Health Sciences, Aston University
  • Aston University
  • Norwich Medical School
  • University College London
  • University of Hull
  • Birmingham and Solihull Mental Health Foundation NHS Trust, UK
  • Birmingham and Solihull Mental Health Foundation Trust
  • Research Department of Primary Care and Population Health, UCL, London.
  • National Centre for Mental Health
  • Faculty of Health and Life Sciences, Oxford Brookes University
  • Norwich Clinical Trials Unit, Norwich


Background: “Behaviour that Challenges” is common in people living with dementia, resident in care homes and historically has been treated with anti-psychotics. However, such usage is associated with 1800 potentially avoidable deaths annually in the UK. This study investigated the feasibility of a full clinical trial of a specialist dementia care pharmacist medication review combined with a health psychology intervention for care staff to limit the use of psychotropics.

This paper focuses on feasibility; including recruitment and retention, implementation of medication change recommendations and the experiences and expectations of care staff.

Methods: West Midlands care homes and individuals meeting the inclusion criteria (dementia diagnosis; medication for behaviour that challenges), or their personal consultee, were approached for consent.

A specialist pharmacist reviewed medication. Care home staff received an educational behaviour change intervention in a three-hour session promoting person-centred care. Primary healthcare staff received a modified version of the training.

The primary outcome measure was the Neuropsychiatric Inventory-Nursing Home version at 3 months. Other outcomes included quality of life, cognition, health economics and prescribed medication. A qualitative evaluation explored expectations and experiences of care staff.

Results: Five care homes and 34 of 108 eligible residents (31.5%) were recruited, against an original target of 45 residents across 6 care homes. Medication reviews were conducted for 29 study participants (85.3%) and the pharmacist recommended stopping or reviewing medication in 21 cases (72.4%). Of the recommendations made, 57.1% (12 of 21) were implemented, and implementation (discontinuation) took a mean of 98.4 days. In total, 164 care staff received training and 21 were interviewed.

Care staff reported a positive experience of the intervention and post intervention adopting a more holistic patient-centred approach.

Conclusions: The intervention contained two elements; staff training and medication review. It was feasible to implement the staff training, and the training appeared to increase the ability and confidence of care staff to manage behaviour that challenges without the need for medication. The medication review would require significant modification for full trial partly related to the relatively limited uptake of the recommendations made, and delay in implementation.

Trial registration: ISRCTN58330068. Registered 15 October 2017. Retrospectively registered


Original languageEnglish
Article number340
Number of pages11
JournalBMC Psychiatry
Publication statusPublished - 19 Oct 2018


  • Dementia, Primary care, Care homes, Pharmacy, Medication review, Behaviour that challenges