Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound

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Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound. / Lempesis, Ioannis G; Goossens, Gijs H; Manolopoulos, Konstantinos N.

In: Adipocyte, Vol. 10, No. 1, 2021, p. 119-123.

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@article{42f9782938ce49f78c907b8de9ffebd7,
title = "Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound",
abstract = "Adipose tissue blood flow (ATBF) is an important determinant of adipose tissue (AT) function. 133Xenon wash-out technique is considered the gold-standard for human ATBF measurements. However, decreasing 133Xenon clinical use and costly production and preservation, make alternative (non-invasive) methods necessary. Here, we explored percutaneous Doppler ultrasound as a proxy method to quantify intravascular subcutaneous abdominal and femoral ATBF in humans (n= 17). Both fasting ATBF and the postprandial increase in ATBF were significantly higher in abdominal compared to femoral AT. Although anatomical variations in vein location and depot thickness may impact feasibility, we demonstrate that Doppler ultrasound detects the expected depot-differences and postprandial increase in ATBF in healthy individuals. This method warrants further investigation in other populations and metabolic conditions.",
author = "Lempesis, {Ioannis G} and Goossens, {Gijs H} and Manolopoulos, {Konstantinos N}",
year = "2021",
doi = "10.1080/21623945.2021.1888471",
language = "English",
volume = "10",
pages = "119--123",
journal = "Adipocyte",
issn = "2162-3945",
publisher = "Taylor & Francis Open Access",
number = "1",

}

RIS

TY - JOUR

T1 - Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound

AU - Lempesis, Ioannis G

AU - Goossens, Gijs H

AU - Manolopoulos, Konstantinos N

PY - 2021

Y1 - 2021

N2 - Adipose tissue blood flow (ATBF) is an important determinant of adipose tissue (AT) function. 133Xenon wash-out technique is considered the gold-standard for human ATBF measurements. However, decreasing 133Xenon clinical use and costly production and preservation, make alternative (non-invasive) methods necessary. Here, we explored percutaneous Doppler ultrasound as a proxy method to quantify intravascular subcutaneous abdominal and femoral ATBF in humans (n= 17). Both fasting ATBF and the postprandial increase in ATBF were significantly higher in abdominal compared to femoral AT. Although anatomical variations in vein location and depot thickness may impact feasibility, we demonstrate that Doppler ultrasound detects the expected depot-differences and postprandial increase in ATBF in healthy individuals. This method warrants further investigation in other populations and metabolic conditions.

AB - Adipose tissue blood flow (ATBF) is an important determinant of adipose tissue (AT) function. 133Xenon wash-out technique is considered the gold-standard for human ATBF measurements. However, decreasing 133Xenon clinical use and costly production and preservation, make alternative (non-invasive) methods necessary. Here, we explored percutaneous Doppler ultrasound as a proxy method to quantify intravascular subcutaneous abdominal and femoral ATBF in humans (n= 17). Both fasting ATBF and the postprandial increase in ATBF were significantly higher in abdominal compared to femoral AT. Although anatomical variations in vein location and depot thickness may impact feasibility, we demonstrate that Doppler ultrasound detects the expected depot-differences and postprandial increase in ATBF in healthy individuals. This method warrants further investigation in other populations and metabolic conditions.

U2 - 10.1080/21623945.2021.1888471

DO - 10.1080/21623945.2021.1888471

M3 - Article

C2 - 33591224

VL - 10

SP - 119

EP - 123

JO - Adipocyte

JF - Adipocyte

SN - 2162-3945

IS - 1

ER -