Making sense of low oxygen sensing
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
Plant-specific group VII Ethylene Response Factor (ERF) transcription factors have emerged as pivotal regulators of flooding and low oxygen responses. In rice (Oryza sativa), these proteins regulate contrasting strategies of flooding survival. Recent studies on Arabidopsis thaliana group VII ERFs show they are stabilized under hypoxia but destabilized under oxygen-replete conditions via the N-end rule pathway of targeted proteolysis. Oxygen-dependent sequestration at the plasma membrane maintains at least one of these proteins, RAP2.12, under normoxia. Remarkably, SUB1A, the rice group VII ERF that enables prolonged submergence tolerance, appears to evade oxygen-regulated N-end rule degradation. We propose that the turnover of group VII ERFs is of ecological relevance in wetland species and might be manipulated to improve flood tolerance of crops.
Copyright Â© 2011 Elsevier Ltd. All rights reserved.
|Number of pages||10|
|Journal||Trends in Plant Science|
|Early online date||24 Jan 2012|
|Publication status||Published - Mar 2012|
- Animals, Arabidopsis, Arabidopsis Proteins, Floods, Humans, Oxygen, Stress, Physiological, Wetlands