Magnetic resonance imaging based functional imaging in paediatric oncology
Research output: Contribution to journal › Review article › peer-review
- Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Department of Paediatric Oncology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: email@example.com.
- Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Department of Paediatric Oncology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: S.K.Gill.firstname.lastname@example.org.
- The Birmingham Children’s Hospital NHS Foundation Trust
- University of Birmingham
Imaging is central to management of solid tumours in children. Conventional magnetic resonance imaging (MRI) is the standard imaging modality for tumours of the central nervous system (CNS) and limbs and is increasingly used in the abdomen. It provides excellent structural detail, but imparts limited information about tumour type, aggressiveness, metastatic potential or early treatment response. MRI based functional imaging techniques, such as magnetic resonance spectroscopy, diffusion and perfusion weighted imaging, probe tissue properties to provide clinically important information about metabolites, structure and blood flow. This review describes the role of and evidence behind these functional imaging techniques in paediatric oncology and implications for integrating them into routine clinical practice.
|Number of pages||15|
|Journal||European Journal of Cancer|
|Publication status||Published - Feb 2017|
- Biomarkers, Tumor, Central Nervous System Neoplasms, Child, Diffusion Magnetic Resonance Imaging, Humans, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Neoplasms, Journal Article, Review, Research Support, Non-U.S. Gov't