Macrocyclic Metal Complex-DNA Conjugates for Electrochemical Sensing of Single Nucleobase Changes in DNA
Research output: Contribution to journal › Article › peer-review
- Polish Acad Sci
The direct incorporation of macrocyclic cyclidene complexes into DNA via automated synthesis results in a new family of metal-functionalized DNA derivatives that readily demonstrate their utility through the ability of one redox-active copper(II)-containing strand to distinguish electrochemically between all four canonical DNA nucleobases at a single site within a target sequence of DNA.
|Journal||Journal of the American Chemical Society|
|Early online date||22 Dec 2015|
|Publication status||Published - 15 Jan 2016|