Lupus nephritis management guidelines compared

Research output: Contribution to journalArticlepeer-review


  • Suzanne Wilhelmus
  • Ingeborg M Bajema
  • George K Bertsias
  • Dimitrios T Boumpas
  • Liz Lightstone
  • Vladimir Tesar
  • David R Jayne

Colleges, School and Institutes


In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis. These guidelines are European, American and internationally based, with one separate guideline for children. They offer information on different aspects of the management of lupus nephritis including induction and maintenance treatment of the different histological classes, adjunctive treatment, monitoring of the patient, definitions of response and relapse, indications for (repeat) renal biopsy, and additional challenges such as the presence of vascular complications, the pregnant SLE patient, treatment in children and adolescents and considerations about end-stage renal disease and transplantation. In this review, we summarize the guidelines, determine the common ground between them, highlight the differences and discuss recent literature.

Bibliographic note

© The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.


Original languageEnglish
JournalNephrology, Dialysis, Transplantation
Publication statusPublished - 28 Apr 2015