Localised cutaneous microvascular adaptation to exercise training in humans
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
- University of Western Australia
- Liverpool John Moores University
- Radboud University
- Research Institute for Sport and Exercise Sciences
- Department of Sports Science
- Aspire Academy
Purpose: Exercise training induces adaptation in conduit and resistance arteries in humans, partly as a consequence of repeated elevation in blood flow and shear stress. The stimuli associated with intrinsic cutaneous microvascular adaptation to exercise training have been less comprehensively studied.
Methods: We studied 14 subjects who completed 8-weeks cycle ergometer training, with partial cuff inflation on one forearm to unilaterally attenuate cutaneous blood flow responses during each exercise-training bout. Before and after training, bilateral forearm skin microvascular dilation was determined using cutaneous vascular conductance (CVC: skin flux/blood pressure) responses to gradual localised heater disk stimulation performed at rest (33, 40, 42 and 44 °C).
Results: Cycle exercise induced significant increases in forearm cutaneous flux and temperature, which were attenuated in the cuffed arm (2-way ANOVA interaction-effect; P OpenSPiltSPi 0.01). We found that forearm CVC at 42 and 44 °C was significantly lower in the uncuffed arm following 8-weeks of cycle training (P OpenSPiltSPi 0.01), whereas no changes were apparent in the contralateral cuffed arm (P = 0.77, interaction-effect P = 0.01).
Conclusions: Lower limb exercise training in healthy young men leads to lower CVC-responses to a local heating stimulus, an adaptation mediated, at least partly, by a mechanism related to episodic increases in skin blood flow and/or skin temperature.
|Number of pages||9|
|Journal||European Journal of Applied Physiology|
|Early online date||7 Feb 2018|
|Publication status||Published - 1 Apr 2018|
- Blood flow, Exercise training, Skin microcirculation