Local activation time derived from stored EGM is associated with failure of antitachycardia pacing in patients with implantable defibrillator.

Research output: Contribution to journalArticle

Standard

Local activation time derived from stored EGM is associated with failure of antitachycardia pacing in patients with implantable defibrillator. / Lim, Hoong; Lencioni, M; Marshall, H.

In: Pacing and Clinical Electrophysiology, Vol. 33, No. 5, 01.05.2010, p. 549-52.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Bibtex

@article{04e28cc0c2a247e7af00495436c63859,
title = "Local activation time derived from stored EGM is associated with failure of antitachycardia pacing in patients with implantable defibrillator.",
abstract = "BACKGROUND Antitachycardia pacing (ATP) is an effective treatment of ventricular tachycardia (VT). However, persistent failure of ATP in some patients is well recognized. METHODS A method of deriving the local activation time from stored intracardiac electrograms in implantable cardioverter defibrillators is described. Using a case-control design, the local activation times were compared between patients with persistent unsuccessful ATP with comparable controls with successful ATP. RESULTS The local activation times during VT in patients with failed ATP were longer at 120-180 ms compared with corresponding control patients with successful ATP (60-80 ms). The local activation time expressed as a proportion of VT cycle length in patients with failed ATP compared with patients with successful ATP were 0.40 +/- 0.08 versus 0.19 +/- 0.08 (P = 0.012). CONCLUSION A novel method of deriving local activation time is described, and delayed local activation time may explain failure of ATP in terminating VT in some patients.",
author = "Hoong Lim and M Lencioni and H Marshall",
year = "2010",
month = may,
day = "1",
doi = "10.1111/j.1540-8159.2009.02638.x",
language = "English",
volume = "33",
pages = "549--52",
journal = "Pacing and Clinical Electrophysiology",
issn = "0147-8389",
publisher = "Wiley",
number = "5",

}

RIS

TY - JOUR

T1 - Local activation time derived from stored EGM is associated with failure of antitachycardia pacing in patients with implantable defibrillator.

AU - Lim, Hoong

AU - Lencioni, M

AU - Marshall, H

PY - 2010/5/1

Y1 - 2010/5/1

N2 - BACKGROUND Antitachycardia pacing (ATP) is an effective treatment of ventricular tachycardia (VT). However, persistent failure of ATP in some patients is well recognized. METHODS A method of deriving the local activation time from stored intracardiac electrograms in implantable cardioverter defibrillators is described. Using a case-control design, the local activation times were compared between patients with persistent unsuccessful ATP with comparable controls with successful ATP. RESULTS The local activation times during VT in patients with failed ATP were longer at 120-180 ms compared with corresponding control patients with successful ATP (60-80 ms). The local activation time expressed as a proportion of VT cycle length in patients with failed ATP compared with patients with successful ATP were 0.40 +/- 0.08 versus 0.19 +/- 0.08 (P = 0.012). CONCLUSION A novel method of deriving local activation time is described, and delayed local activation time may explain failure of ATP in terminating VT in some patients.

AB - BACKGROUND Antitachycardia pacing (ATP) is an effective treatment of ventricular tachycardia (VT). However, persistent failure of ATP in some patients is well recognized. METHODS A method of deriving the local activation time from stored intracardiac electrograms in implantable cardioverter defibrillators is described. Using a case-control design, the local activation times were compared between patients with persistent unsuccessful ATP with comparable controls with successful ATP. RESULTS The local activation times during VT in patients with failed ATP were longer at 120-180 ms compared with corresponding control patients with successful ATP (60-80 ms). The local activation time expressed as a proportion of VT cycle length in patients with failed ATP compared with patients with successful ATP were 0.40 +/- 0.08 versus 0.19 +/- 0.08 (P = 0.012). CONCLUSION A novel method of deriving local activation time is described, and delayed local activation time may explain failure of ATP in terminating VT in some patients.

U2 - 10.1111/j.1540-8159.2009.02638.x

DO - 10.1111/j.1540-8159.2009.02638.x

M3 - Article

C2 - 20015127

VL - 33

SP - 549

EP - 552

JO - Pacing and Clinical Electrophysiology

JF - Pacing and Clinical Electrophysiology

SN - 0147-8389

IS - 5

ER -