TY - JOUR
T1 - Lip hypertrophy secondary to cyclosporin treatment
AU - Cansick, JC
AU - Hulton, Sally-Anne
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Gingival hypertrophy is a well-documented side effect of cyclosporin therapy, but severe lip enlargement is less frequently recognised. This can lead to poor body image, low self-esteem and non-compliance, especially in the older childhood and adolescent age groups. We describe two paediatric renal transplant recipients who had marked lip hypertrophy as a consequence of cyclosporin (Neoral) treatment. On changing the immunosuppression to tacrolimus (Prograf), this resolved. We recommend that a change in immunosuppressant therapy be considered in children with significant changes to facial appearance.
AB - Gingival hypertrophy is a well-documented side effect of cyclosporin therapy, but severe lip enlargement is less frequently recognised. This can lead to poor body image, low self-esteem and non-compliance, especially in the older childhood and adolescent age groups. We describe two paediatric renal transplant recipients who had marked lip hypertrophy as a consequence of cyclosporin (Neoral) treatment. On changing the immunosuppression to tacrolimus (Prograf), this resolved. We recommend that a change in immunosuppressant therapy be considered in children with significant changes to facial appearance.
UR - http://www.scopus.com/inward/record.url?scp=0037677704&partnerID=8YFLogxK
U2 - 10.1007/s00467-003-1144-y
DO - 10.1007/s00467-003-1144-y
M3 - Article
C2 - 12750983
SN - 1432-198X
SN - 1432-198X
SN - 1432-198X
SN - 1432-198X
VL - 18
SP - 710
EP - 711
JO - Pediatric Nephrology
JF - Pediatric Nephrology
ER -