Linked Metabolites: A tool for the construction of directed metabolic graphs.
Research output: Contribution to journal › Article
Authors
Colleges, School and Institutes
Abstract
Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
Details
Original language | English |
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Pages (from-to) | 340-9 |
Number of pages | 10 |
Journal | Computers in Biology and Medicine |
Volume | 40 |
Issue number | 3 |
Publication status | Published - 5 Feb 2010 |
Keywords
- KEGG, Directed graphs, Metabolic pathways, All simple paths search, Metabolomics