Linked Metabolites: A tool for the construction of directed metabolic graphs.

Research output: Contribution to journalArticle


Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.


Original languageEnglish
Pages (from-to)340-9
Number of pages10
JournalComputers in Biology and Medicine
Issue number3
Publication statusPublished - 5 Feb 2010


  • KEGG, Directed graphs, Metabolic pathways, All simple paths search, Metabolomics