Issues surrounding standard cytotoxicity testing for assessing activity of non-covalent DNA-binding metallo-drugs
Research output: Contribution to journal › Article
Colleges, School and Institutes
Investigating the methods commonly used to evaluate in vitro cytotoxicity of novel compounds, specifically non-covalent DNA binders, identifies that these methods may not be appropriate. The level of anticancer activity depends not only on the incubation time but also on the absolute amount (number of moles) of drug compound applied, rather than the concentration.
|Number of pages||3|
|Publication status||Published - 1 Jan 2010|