Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease?

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Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease? / Jia, Wenjing; Whitehead, Rebekah; Griffiths, Lesley; Dawson, C; Waring, Rosemary; Ramsden, David; Hunter, JO; Cole, Jeffrey.

In: FEMS Microbiology Letters, Vol. 310, No. 2, 01.09.2010, p. 138-144.

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@article{47de8a59a96342df8092a5aa9064c9e9,
title = "Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease?",
abstract = "Reports that bacteria within the Firmicutes phylum, especially the species Faecalibacterium prausnitzii, are less abundant in Crohn{\textquoteright}s disease (CD) patients and supernatants from cultures of this bacterium are anti-inflammatory prompted the investigation of the possible correlations between the abundance of F.prausnitzii and the response to treatment in patients with gut diseases and healthy controls. In a randomized, double-blind trial, faeces were collected from healthy volunteers, and from patients with active CD, ulcerative colitis (UC) and irritable bowel syndrome before and after treatment. The levels of F. prausnitzii DNA in faecal suspensions were determined by PCR. Treatment by an elemental diet was effective, resulting in decreases in both the Harvey and Bradshaw index (P",
keywords = "Crohn's disease, ulcerative colitis, Faecalibacterium prausnitzii, irritable bowel syndrome, faecal bacteria, butyrate",
author = "Wenjing Jia and Rebekah Whitehead and Lesley Griffiths and C Dawson and Rosemary Waring and David Ramsden and JO Hunter and Jeffrey Cole",
year = "2010",
month = sep,
day = "1",
doi = "10.1111/j.1574-6968.2010.02057.x",
language = "English",
volume = "310",
pages = "138--144",
journal = "FEMS Microbiology Letters",
issn = "0378-1097",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease?

AU - Jia, Wenjing

AU - Whitehead, Rebekah

AU - Griffiths, Lesley

AU - Dawson, C

AU - Waring, Rosemary

AU - Ramsden, David

AU - Hunter, JO

AU - Cole, Jeffrey

PY - 2010/9/1

Y1 - 2010/9/1

N2 - Reports that bacteria within the Firmicutes phylum, especially the species Faecalibacterium prausnitzii, are less abundant in Crohn’s disease (CD) patients and supernatants from cultures of this bacterium are anti-inflammatory prompted the investigation of the possible correlations between the abundance of F.prausnitzii and the response to treatment in patients with gut diseases and healthy controls. In a randomized, double-blind trial, faeces were collected from healthy volunteers, and from patients with active CD, ulcerative colitis (UC) and irritable bowel syndrome before and after treatment. The levels of F. prausnitzii DNA in faecal suspensions were determined by PCR. Treatment by an elemental diet was effective, resulting in decreases in both the Harvey and Bradshaw index (P

AB - Reports that bacteria within the Firmicutes phylum, especially the species Faecalibacterium prausnitzii, are less abundant in Crohn’s disease (CD) patients and supernatants from cultures of this bacterium are anti-inflammatory prompted the investigation of the possible correlations between the abundance of F.prausnitzii and the response to treatment in patients with gut diseases and healthy controls. In a randomized, double-blind trial, faeces were collected from healthy volunteers, and from patients with active CD, ulcerative colitis (UC) and irritable bowel syndrome before and after treatment. The levels of F. prausnitzii DNA in faecal suspensions were determined by PCR. Treatment by an elemental diet was effective, resulting in decreases in both the Harvey and Bradshaw index (P

KW - Crohn's disease

KW - ulcerative colitis

KW - Faecalibacterium prausnitzii

KW - irritable bowel syndrome

KW - faecal bacteria

KW - butyrate

U2 - 10.1111/j.1574-6968.2010.02057.x

DO - 10.1111/j.1574-6968.2010.02057.x

M3 - Article

C2 - 20695899

VL - 310

SP - 138

EP - 144

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

SN - 0378-1097

IS - 2

ER -