Is It Time to Beta Block the Septic Patient?

P. Pemberton, T. Veenith, C. Snelson, T. Whitehouse

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)
87 Downloads (Pure)

Abstract

Beta blockers are some of the most studied drugs in the pharmacopoeia. They are already widely used in medicine for treating hypertension, chronic heart failure, tachyarrhythmias, and tremor. Whilst their use in the immediate perioperative patient has been questioned, the use of esmolol in the patients with established septic shock has been recently reported to have favourable outcomes. In this paper, we review the role of the adrenergic system in sepsis and the evidence for the use of beta stimulation and beta blockers from animal models to critically ill patients.
Original languageEnglish
Article number424308
Number of pages7
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - 18 Oct 2015

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