Is aldehyde dehydrogenase 2 a credible genetic instrument for alcohol use in Mendelian randomization analysis in Southern Chinese men?

Research output: Contribution to journalArticlepeer-review


  • Shiu Lun Au Yeung
  • Chaoqiang Jiang
  • Bin Liu
  • Weisen Zhang
  • Tai Hing Lam
  • Gabriel M Leung
  • C Mary Schooling


Mendelian randomization studies provide a means of assessing causal relations without interventions, but require valid genetic instruments. We assessed the credibility of aldehyde dehydrogenase 2 (ALDH2) as a genetic instrument for alcohol use in Southern Chinese men.


Original languageEnglish
Pages (from-to)318-28
Number of pages11
JournalInternational Journal of Epidemiology
Issue number1
Publication statusPublished - Feb 2013