Investigation of orbitofrontal sulcogyral pattern in chronic schizophrenia

Research output: Contribution to journalArticlepeer-review


  • Vanessa L Cropley
  • Cali F Bartholomeusz
  • Peter Wu
  • Tina Proffitt
  • Warrick J Brewer
  • Patricia M Desmond
  • Dennis Velakoulis
  • Christos Pantelis

Colleges, School and Institutes


Abnormalities of orbitofrontal cortex (OFC) pattern type distribution have been associated with schizophrenia-spectrum disorders. We investigated OFC pattern type in a large sample of chronic schizophrenia patients and healthy controls. We found an increased frequency of Type II but no difference in Type I or III folding pattern in the schizophrenia group in comparison to controls. Further large studies are required to investigate the diagnostic specificity of altered OFC pattern type and to confirm the distribution of pattern type in the normal population.

Bibliographic note

Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.


Original languageEnglish
JournalPsychiatry Research
Early online date5 Sep 2015
Publication statusE-pub ahead of print - 5 Sep 2015


  • Orbitofrontal cortex, Pattern type, Schizophrenia