Investigation of community carriage rates of Clostridium difficile and Hungatella hathewayi in healthy volunteers from four regions of England

Research output: Contribution to journalArticle


  • S. E. Manzoor
  • C. A. M. McNulty
  • D. Nakiboneka-Ssenabulya
  • D. M. Lecky

Colleges, School and Institutes

External organisations

  • Public Health Laboratory Birmingham, Heart of England Foundation Trust
  • Primary Care Unit, Public Health England, Gloucester, Gloucestershire Royal Hospital


Faecal samples from 1365 healthy asymptomatic volunteers from four regions in England were screened for the presence of Clostridium difficile between December 2013 and July 2014. The carriage rate of C. difficile in healthy patients was 0.5%, which is lower than previously reported. This study demonstrates that the true community reservoir of C. difficile in the healthy UK population is very low and is, therefore, unlikely to be a reservoir for infections diagnosed in the hospital setting.


Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalThe Journal of hospital infection
Issue number2
Early online date23 May 2017
Publication statusPublished - Oct 2017


  • Adult, Carrier State/microbiology, Clostridium/isolation & purification, Clostridium Infections/diagnosis, Clostridium difficile/isolation & purification, England/epidemiology, Feces/microbiology, Healthy Volunteers, Humans, Polymerase Chain Reaction, State Medicine, Young Adult