Intraocular immune mechanisms in Uveitis

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Intraocular immune mechanisms in Uveitis. / Curnow, S. John; Denniston, Alastair K.O.; Murray, Philip I.; Wallace, Graham R.

In: Current Immunology Reviews, Vol. 7, No. 3, 01.08.2011, p. 350-359.

Research output: Contribution to journalReview articlepeer-review

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@article{f47cc5326d0541ea9ac1c6eacfeeae15,
title = "Intraocular immune mechanisms in Uveitis",
abstract = "Uveitis describes a group of sight threatening disorders characterized by breakdown of the blood-ocular barriers, cellular infiltration and tissue damage. Uveitis can be categorized into different groups based on site of inflammation in the eye, the onset, duration and course of disease, and causative agent. Whether these different forms of uveitis have different aetiologies is of interest with regards to prognosis and therapy in individual patients. In this review, we shall discuss mechanisms of blood-ocular barrier breakdown, cellular responses and the molecules involved in different uveitis conditions.",
keywords = "Autoimmune, Chemokines, Cytokines, Inflammation, Uveitis",
author = "Curnow, {S. John} and Denniston, {Alastair K.O.} and Murray, {Philip I.} and Wallace, {Graham R.}",
year = "2011",
month = aug,
day = "1",
doi = "10.2174/157339511796196647",
language = "English",
volume = "7",
pages = "350--359",
journal = "Current Immunology Reviews",
issn = "1573-3955",
publisher = "Bentham Science Publishers",
number = "3",

}

RIS

TY - JOUR

T1 - Intraocular immune mechanisms in Uveitis

AU - Curnow, S. John

AU - Denniston, Alastair K.O.

AU - Murray, Philip I.

AU - Wallace, Graham R.

PY - 2011/8/1

Y1 - 2011/8/1

N2 - Uveitis describes a group of sight threatening disorders characterized by breakdown of the blood-ocular barriers, cellular infiltration and tissue damage. Uveitis can be categorized into different groups based on site of inflammation in the eye, the onset, duration and course of disease, and causative agent. Whether these different forms of uveitis have different aetiologies is of interest with regards to prognosis and therapy in individual patients. In this review, we shall discuss mechanisms of blood-ocular barrier breakdown, cellular responses and the molecules involved in different uveitis conditions.

AB - Uveitis describes a group of sight threatening disorders characterized by breakdown of the blood-ocular barriers, cellular infiltration and tissue damage. Uveitis can be categorized into different groups based on site of inflammation in the eye, the onset, duration and course of disease, and causative agent. Whether these different forms of uveitis have different aetiologies is of interest with regards to prognosis and therapy in individual patients. In this review, we shall discuss mechanisms of blood-ocular barrier breakdown, cellular responses and the molecules involved in different uveitis conditions.

KW - Autoimmune

KW - Chemokines

KW - Cytokines

KW - Inflammation

KW - Uveitis

UR - http://www.scopus.com/inward/record.url?scp=79959938484&partnerID=8YFLogxK

U2 - 10.2174/157339511796196647

DO - 10.2174/157339511796196647

M3 - Review article

AN - SCOPUS:79959938484

VL - 7

SP - 350

EP - 359

JO - Current Immunology Reviews

JF - Current Immunology Reviews

SN - 1573-3955

IS - 3

ER -