Intraocular immune mechanisms in Uveitis

Research output: Contribution to journalReview article

Abstract

Uveitis describes a group of sight threatening disorders characterized by breakdown of the blood-ocular barriers, cellular infiltration and tissue damage. Uveitis can be categorized into different groups based on site of inflammation in the eye, the onset, duration and course of disease, and causative agent. Whether these different forms of uveitis have different aetiologies is of interest with regards to prognosis and therapy in individual patients. In this review, we shall discuss mechanisms of blood-ocular barrier breakdown, cellular responses and the molecules involved in different uveitis conditions.

Details

Original languageEnglish
Pages (from-to)350-359
Number of pages10
JournalCurrent Immunology Reviews
Volume7
Issue number3
Publication statusPublished - 1 Aug 2011

Keywords

  • Autoimmune, Chemokines, Cytokines, Inflammation, Uveitis

ASJC Scopus subject areas