Interventions for mental health problems in children and adults with severe intellectual disabilities: a systematic review

Research output: Contribution to journalArticle

Authors

  • Leen Vereenooghe
  • Samantha Flynn
  • Richard P Hastings
  • Dawn Adams
  • Umesh Chauhan
  • Sally-Ann Cooper
  • Nick Gore
  • Chris Hatton
  • Kerry Hood
  • Andrew Jahoda
  • Peter E Langdon
  • Rachel McNamara
  • Ashok Roy
  • Vasiliki Totsika
  • Jane Waite

Colleges, School and Institutes

External organisations

  • Faculty of Psychology and Sports Science, Bielefeld University, Bielefeld, Germany.
  • Centre for Educational Development, Appraisal and Research, University of Warwick, Coventry, UK.
  • Centre for Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
  • Autism Centre of Excellence, Griffith University, Brisbane, Queensland, Australia.
  • University of Central Lancashire
  • University of Glasgow
  • University of Kent
  • Lancaster University
  • Cardiff University
  • School of Psychology, University of Birmingham
  • Brooklands Hospital, Coventry and Warwickshire Partnership NHS Trust, Coventry, UK.
  • Centre for Education Studies, University of Warwick, Coventry, UK.
  • Aston University

Abstract

OBJECTIVE: Mental health problems are more prevalent in people with than without intellectual disabilities, yet treatment options have received little attention. The aim of this study was to identify and evaluate the effectiveness of pharmacological and psychological interventions in the treatment of mental health problems in children and adults with severe and profound intellectual disabilities, given their difficulties in accessing standard mental health interventions, particularly talking therapies, and difficulties reporting drug side effects.

DESIGN: A systematic review using electronic searches of PsycINFO, PsycTESTS, EMBASE, MEDLINE, CINAHL, ERIC, ASSIA, Science Citation Index, Social Science Citation Index and CENTRAL was conducted to identify eligible intervention studies. Study selection, data extraction and quality appraisal were performed by two independent reviewers.

PARTICIPANTS: Study samples included at least 70% children and/or adults with severe or profound intellectual disabilities or reported the outcomes of this subpopulation separate from participants with other levels of intellectual disabilities.

INTERVENTIONS: Eligible intervention studies evaluated a psychological or pharmacological intervention using a control condition or pre-post design.

OUTCOMES: Symptom severity, frequency or other quantitative dimension (e.g., impact), as assessed with standardised measures of mental health problems.

RESULTS: We retrieved 41 232 records, reviewed 573 full-text articles and identified five studies eligible for inclusion: three studies evaluating pharmacological interventions, and two studies evaluating psychological interventions. Study designs ranged from double-blind placebo controlled crossover trials to single-case experimental reversal designs. Quality appraisals of this very limited literature base revealed good experimental control, poor reporting standards and a lack of follow-up data.

CONCLUSIONS: Mental ill health requires vigorous treatment, yet the current evidence base is too limited to identify with precision effective treatments specifically for children or adults with severe and profound intellectual disabilities. Clinicians therefore must work on the basis of general population evidence, while researchers work to generate more precise evidence for people with severe and profound intellectual disabilities.

PROSPERO REGISTRATION NUMBER: CRD 42015024469.

Details

Original languageEnglish
Pages (from-to)e021911
JournalBMJ open
Volume8
Issue number6
Publication statusPublished - 19 Jun 2018