Abstract
Cationized ferritin (200 micrograms ml-1) causes a reduction in both spontaneous and evoked transmitter release at the frog neuromuscular junction. The reduction in EPP amplitude probably reflects reduced Ca2+ -influx since full recovery can be achieved by elevation of [Ca2+]o. The effect on MEPP frequency is independent of [Ca2+]o and may well reflect a direct effect on exocytosis.
| Original language | English |
|---|---|
| Pages (from-to) | 629-32 |
| Number of pages | 4 |
| Journal | Experimental Brain Research |
| Volume | 59 |
| Issue number | 3 |
| Publication status | Published - 1985 |
Keywords
- Animals
- Calcium
- Electrophysiology
- Ferritins
- Ligands
- Microscopy, Electron
- Motor Endplate
- Nerve Endings
- Neural Inhibition
- Neuromuscular Junction
- Neurotransmitter Agents
- Rana temporaria
- Time Factors