Inhibition of quantal transmitter release by the polycationic ligand cationized ferritin
Research output: Contribution to journal › Article
Colleges, School and Institutes
Cationized ferritin (200 micrograms ml-1) causes a reduction in both spontaneous and evoked transmitter release at the frog neuromuscular junction. The reduction in EPP amplitude probably reflects reduced Ca2+ -influx since full recovery can be achieved by elevation of [Ca2+]o. The effect on MEPP frequency is independent of [Ca2+]o and may well reflect a direct effect on exocytosis.
|Number of pages||4|
|Journal||Experimental Brain Research|
|Publication status||Published - 1985|
- Animals, Calcium, Electrophysiology, Ferritins, Ligands, Microscopy, Electron, Motor Endplate, Nerve Endings, Neural Inhibition, Neuromuscular Junction, Neurotransmitter Agents, Rana temporaria, Time Factors