Information-theoretic method for wavelength selection in bioluminescence tomography

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Information-theoretic method for wavelength selection in bioluminescence tomography. / Basevi, H.R.A.; Guggenheim, J.A.; Dehghani, H.; Styles, I.B.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799 2013.

Research output: Chapter in Book/Report/Conference proceedingChapter

Harvard

Basevi, HRA, Guggenheim, JA, Dehghani, H & Styles, IB 2013, Information-theoretic method for wavelength selection in bioluminescence tomography. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8799. https://doi.org/10.1117/12.2033320

APA

Vancouver

Basevi HRA, Guggenheim JA, Dehghani H, Styles IB. Information-theoretic method for wavelength selection in bioluminescence tomography. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799. 2013 https://doi.org/10.1117/12.2033320

Author

Basevi, H.R.A. ; Guggenheim, J.A. ; Dehghani, H. ; Styles, I.B. / Information-theoretic method for wavelength selection in bioluminescence tomography. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799 2013.

Bibtex

@inbook{10fad5500775496ca4a6ecf6f107fc8c,
title = "Information-theoretic method for wavelength selection in bioluminescence tomography",
abstract = "Practical imaging constraints restrict the number of wavelengths that can be measured in a single Bioluminescence Tomography imaging session, but it is unclear which set of measurement wavelengths is optimal, in the sense of providing the most information about the bioluminescent source. Mutual Information was used to integrate knowledge of the type of bioluminescent source likely to be present, the optical properties of tissue and physics of light propagation, and the noise characteristics of the imaging system, in order to quantify the information contained in measurements at different sets of wavelengths. The approach was applied to a two-dimensional simulation of Bioluminescence Tomography imaging of a mouse, and the results indicate that different wavelengths and sets of wavelengths contain different amounts of information. When imaging at a single wavelength, 580nm was found to be optimal, and when imaging at two wavelengths, 570nm and 580nm were found to be optimal. Examination of the dispersion of the posterior distributions for single wavelengths suggests that information regarding the location of the centre of the bioluminescence distribution is relatively independent of wavelength, whilst information regarding the width of the bioluminescence distribution is relatively wavelength specific.",
author = "H.R.A. Basevi and J.A. Guggenheim and H. Dehghani and I.B. Styles",
year = "2013",
month = jun,
day = "25",
doi = "10.1117/12.2033320",
language = "English",
isbn = "9780819496485",
volume = "8799",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

RIS

TY - CHAP

T1 - Information-theoretic method for wavelength selection in bioluminescence tomography

AU - Basevi, H.R.A.

AU - Guggenheim, J.A.

AU - Dehghani, H.

AU - Styles, I.B.

PY - 2013/6/25

Y1 - 2013/6/25

N2 - Practical imaging constraints restrict the number of wavelengths that can be measured in a single Bioluminescence Tomography imaging session, but it is unclear which set of measurement wavelengths is optimal, in the sense of providing the most information about the bioluminescent source. Mutual Information was used to integrate knowledge of the type of bioluminescent source likely to be present, the optical properties of tissue and physics of light propagation, and the noise characteristics of the imaging system, in order to quantify the information contained in measurements at different sets of wavelengths. The approach was applied to a two-dimensional simulation of Bioluminescence Tomography imaging of a mouse, and the results indicate that different wavelengths and sets of wavelengths contain different amounts of information. When imaging at a single wavelength, 580nm was found to be optimal, and when imaging at two wavelengths, 570nm and 580nm were found to be optimal. Examination of the dispersion of the posterior distributions for single wavelengths suggests that information regarding the location of the centre of the bioluminescence distribution is relatively independent of wavelength, whilst information regarding the width of the bioluminescence distribution is relatively wavelength specific.

AB - Practical imaging constraints restrict the number of wavelengths that can be measured in a single Bioluminescence Tomography imaging session, but it is unclear which set of measurement wavelengths is optimal, in the sense of providing the most information about the bioluminescent source. Mutual Information was used to integrate knowledge of the type of bioluminescent source likely to be present, the optical properties of tissue and physics of light propagation, and the noise characteristics of the imaging system, in order to quantify the information contained in measurements at different sets of wavelengths. The approach was applied to a two-dimensional simulation of Bioluminescence Tomography imaging of a mouse, and the results indicate that different wavelengths and sets of wavelengths contain different amounts of information. When imaging at a single wavelength, 580nm was found to be optimal, and when imaging at two wavelengths, 570nm and 580nm were found to be optimal. Examination of the dispersion of the posterior distributions for single wavelengths suggests that information regarding the location of the centre of the bioluminescence distribution is relatively independent of wavelength, whilst information regarding the width of the bioluminescence distribution is relatively wavelength specific.

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84881122370&partnerID=8YFLogxK

U2 - 10.1117/12.2033320

DO - 10.1117/12.2033320

M3 - Chapter

AN - SCOPUS:84881122370

SN - 9780819496485

VL - 8799

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -